Analyzing the integration profile of retroviral vectors is a vital step in determining their potential genotoxic effects and developing safer vectors for therapeutic use. Identifying retroviral vector integration sites is also important for retroviral mutagenesis screens. Source…
Web app
G T A T C G C T A SeqMap SeqMap

SeqMap

A tool for identifying viral integration sites from LAM-PCR and LM-PCR…

A tool for identifying viral integration sites from LAM-PCR and LM-PCR analysis. SeqMap will extract vector sequence data then search existing genome databases for matches to the unique sequences…

Web app
G T A T C G C T A High-Througput… High-Througput Insertion Site Analysis Pipeline

HISAP High-Througput Insertion Site Analysis Pipeline

Annotates viral vector insertion site information for a collection of samples.…

Annotates viral vector insertion site information for a collection of samples. HISAP was generated to characterize insertions sites of viral gene therapy vectors, previously amplified with…

Web app
G T A T C G C T A Vector Integration… Vector Integration Site Analysis

VISA Vector Integration Site Analysis

Analyzes next-generation sequencing data for retroviral vector integration…

Analyzes next-generation sequencing data for retroviral vector integration sites (RISs). Sequence reads that contain a provirus are mapped to the human genome, sequence reads that cannot be localized…

Web app
G T A T C G C T A Vector Integration… Vector Integration Site Parallel Analysis

VISPA Vector Integration Site Parallel Analysis

A pipeline for automated integration site identification and annotation based…

A pipeline for automated integration site identification and annotation based on a distributed environment with a simple Galaxy web interface. VISPA was successfully used for the bioinformatics…

Desktop app
G T A T C G C T A VirusFinder VirusFinder

VirusFinder

A software tool for characterizing intra-host viruses through next generation…

A software tool for characterizing intra-host viruses through next generation sequencing (NGS) data. It implements our recently developed algorithm, Virus intEgration site detection through Reference…

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