Tool stats & trends
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|Interface||Web user interface|
|Restrictions to use||None|
|Input data||Plain protein sequence|
- person_outline Jianlin Cheng
Publication for RF-Fold
A Metabolomic Signature of Acute Caloric Restriction
[…] tricarboxylic acid (TCA) cycle (). As expected, CR was associated with a decrease in glucose (fold change 0.84, P = 5.9 × 10−5) and pyruvate (fold change 0.32, P = 9.0 × 10−4), which were restored by RF (fold change 1.14 and 10.8, P = 8.0 × 10−4 and 1.2 × 10−7, respectively) (). Citrate and aconitate were significantly elevated with CR, there was no change in isocitrate or α-ketoglutarate, but a s […]
In vivo probing of nascent RNA structures reveals principles of cotranscriptional folding
[…] 50 -nw 50 -wo 25). The rf-norm tool generates a XML file for each transcript (or for each transcription intermediate/decile in the case of SPET-seq data). XML files for mature RNA were passed to the rf-fold tool of the RNA Framework (using ViennaRNA Package 2.2 with soft constraints ()) to infer mature RNA structures (parameters: -md 600 -nlp). […]
Adaptive local learning in sampling based motion planning for protein folding
[…] ition problem is defined as a binary classification problem of predicting whether or not the unknown fold of the input protein is similar to an already known template from a protein structure library.RF-Fold uses random forests, a highly scalable classification method, to recognize protein folds . A random forest is composed of many decision trees that are each trained on datasets of target-temp […]
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