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riboSNitch prediction software tools | RNA structure data analysis

Ribonucleic acid (RNA) secondary structure prediction continues to be a significant challenge, in particular when attempting to model sequences with less rigidly defined structures, such as messenger and non-coding RNAs. Crucial to interpreting RNA…
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classSNitch
Desktop

classSNitch

Recognizes RNA structure change in large amounts of Selective 20 Hydroxyl…

Recognizes RNA structure change in large amounts of Selective 20 Hydroxyl Acylation by Primer Extension (SHAPE) data. classSNitch provides methods for normalization, noise reduction, and calculating…

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RNAsnp Web…
Web

RNAsnp Web Server

An efficient method to predict the effect of SNPs on local RNA secondary…

An efficient method to predict the effect of SNPs on local RNA secondary structure based on the RNA folding algorithms implemented in the Vienna RNA package.

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RNAmutants
Web

RNAmutants

Provides several efficient tools to compute the ensemble of low-energy…

Provides several efficient tools to compute the ensemble of low-energy secondary structures for all k-mutants of a given RNA sequence, where k is bounded by a user-specified upper bound. In contrast…

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remuRNA
Desktop

remuRNA

Single-nucleotide polymorphisms (SNPs) are often linked to critical phenotypes…

Single-nucleotide polymorphisms (SNPs) are often linked to critical phenotypes such as diseases or responses to vaccines, medications and environmental factors. However, the specific molecular…

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RNAmute
Desktop
Web

RNAmute

A program that is structure based and relies on RNA secondary-structure…

A program that is structure based and relies on RNA secondary-structure prediction has been developed for assisting in RNA mutational analysis. RNAmute has been extended from single-point mutations…

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SNPfold
Desktop

SNPfold

Helps identify RiboSNitches by leveraging GWAS data and an analysis of the mRNA…

Helps identify RiboSNitches by leveraging GWAS data and an analysis of the mRNA structural ensemble. When running SNPfold, the sequence and mutations are required at bare minimum. The user can either…

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RDMAS
Web

RDMAS

An online tool for evaluating structural deleteriousness of single nucleotide…

An online tool for evaluating structural deleteriousness of single nucleotide mutation in RNA genes. Several structure comparison methods have been integrated; sub-optimal structures predicted can be…

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