Ritornello specifications


Unique identifier OMICS_15423
Name Ritornello
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages C++
License GNU General Public License version 3.0
Computer skills Advanced
Version 1.0
Stability Stable
SAMtools, FFTW, boost
Maintained Yes




No version available



  • person_outline Yuval Kluger

Ritornello citation


Ritornello: high fidelity control free chromatin immunoprecipitation peak calling

Nucleic Acids Res
PMCID: 5716106
PMID: 28981893
DOI: 10.1093/nar/gkx799

[…] re and . It is worth noting, however, that when provided controls, the MACS2-I and GEM-I reported peaks also have a strong bimodal shape with less signal in the control sample. This illustrates that Ritornello reliably rescues peaks from low quality samples, while MACS2-I and GEM-I might be able to avoid calling false positive artifacts from low quality samples as well. […]

Ritornello institution(s)
Department of Pathology, Yale University School of Medicine, New Haven, CT, USA; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA; Program of Applied Mathematics, Yale University, New Haven, CT, USA
Ritornello funding source(s)
Supported by National Institute of Health [T15 LM07056], [U54HG006996-03] and [CA-158167, and R01 GM086852].

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