RNA editing site detection bioinformatics tools

RNA editing site identification software tools | RNA sequencing data analysis

RNA editing generates post-transcriptional sequence changes that can be deduced from RNA-seq data, but detection typically requires matched genomic sequence or multiple related expression data sets.

REDItools

Performs investigation of RNA editing from next-generation sequencing (NGS) data. REDItools contains three main scripts to study RNA editing using both RNA-Seq and DNA-Seq data from the same sample/individual or RNA-Seq data alone: (1) REDItoolDnaRNA.py for detecting RNA editing candidates, (2) REDItoolKnown.py for exploring the RNA editing potential of RNA-Seq experiments, and (3) REDItoolDenovo.py for performing de novo detection of RNA editing candidates. It also includes some accessory scripts and allows to annotate all candidate positions using relevant databases.

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