Provides comprehensive information of RNA modifications concerning the chemical structures of modified ribonucleosides, their biosynthetic pathways, RNA-modifying enzymes and location of modified residues in RNA sequences. MODOMICS simplifies literature searches thanks to records cross-referenced to other databases and to selected key publications. It includes a BLAST search of protein sequences and a PARALIGN search of the collected nucleic acid sequences.
Provides a comprehensive listing of post-transcriptionally modified nucleosides from RNA. RNAMDB employs an easy-to-use, searchable interface for obtaining detailed data on the 109 currently known RNA modifications. Each entry provides the chemical structure, common name and symbol, elemental composition and mass, CA registry numbers and index name, phylogenetic source, type of RNA species in which it is found, and references to the first reported structure determination and synthesis. RNAMDB serves as a primary information portal for researchers across the entire spectrum of RNA-related research.
Allows the global investigation of more than 100 RNA modification types and reveals extensive and complex post-transcriptional modifications (PTMs) of RNA. RMBase provides a variety of interfaces and graphic visualizations to facilitate analyses of the massive modification sites in normal tissues and cancer cells. Moreover, this platform assists researchers to discover potential functional roles of RNA modifications hidden in different data.
Assists users in investigating and optimizing methods for reprogramming and differentiation of induced pluripotent stem cells (iPSC). PCBC is a publicly available online collaborative research platform that provides data annotation, documentation, and file provenance. This resource also includes metadata, in vitro and in vivo differentiation, qPCR, RNA-seq, miRNA-seq, copy number variation, and DNA methylation data.
Searches, visualizes and interprets circadian genes and multiple transcriptional and post-transcriptional regulatory. CirGRDB offers a user-friendly web interface that provides bench researchers substantial convenience to explore the underlying regulatory mechanism for oscillating genes and disease-related circadian RNAs. This online resource offers a useful repository for deciphering the regulation of circadian rhythms and provides valuable insights into novel therapies for circadian-related disorders of humans.
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