bookmark RMfam / RNA Motif Families A database of annotated multiple sequence alignments and probabilistic models for a number of RNA motifs. RMfam presents 34 alignments, consensus structures and corresponding probabilistic models of published RNA motifs. For the purposes of this work an RNA motif is a recurring RNA sequence and/or secondary structure found within larger structures that can be modelled by either a covariance model or a profile HMM. RMfam is modelled loosely on the Rfam and Pfam databases and draws a lot of ideas from these resources. We have proven the accuracy using benchmarks, and the utility of this resource for alignment curation, evolutionary analyses and shown that it has some promise for the prediction of RNA function.