RNA structure data analysis software tools
RNA structures can be described at the two-dimensional (2D) and three-dimensional (3D) levels, respectively. A 2D structure is defined by the base pairs contained in the structure. Helices and loops, as defined by the base pairs contained in the structure, can be diagrammatically depicted by an RNA 2D structure. The 2D structure of an RNA provides the structural constraints to the formation of the 3D structure, where helices and loops are assembled in the 3D space. RNA free energy landscape can have multiple free energy minima. Therefore, an RNA can often adopt multiple stable and metastable structures.