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RNA22 specifications


Unique identifier OMICS_04094
Name RNA22
Interface Web user interface
Restrictions to use None
Computer skills Basic
Version 2.0
Stability Stable
Maintained Yes
Wikipedia https://en.wikipedia.org/wiki/RNA22


  • Invertebrates
    • Caenorhabditis elegans
    • Drosophila melanogaster
  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus


  • person_outline Isidore Rigoutsos

Publication for RNA22

RNA22 citations


Telomerase regulation by the long non coding RNA H19 in human acute promyelocytic leukemia cells

Mol Cancer
PMCID: 5923027
PMID: 29703210
DOI: 10.1186/s12943-018-0835-8

[…] codes two conserved miRNAs processed from its first exon, miR-676-5p and miR-675-3p []. Using several in silico bioinformatics web-based analysis including TargetScan (URL:http://www.targetscan.org), RNA22 (URL: https://cm.jefferson.edu/rna22), and miRanda (URL:https://omictools.com/miranda-tool), we found that hTERT mRNA was predicted as a potential, target of miR-675-5p, although poorly conserve […]


MicroRNA 671 3p inhibits the development of breast cancer: A study based on in vitro experiments, in house quantitative polymerase chain reaction and bioinformatics analysis

PMCID: 5919715
PMID: 29620195
DOI: 10.3892/ijo.2018.4339
call_split See protocol

[…] The predicted target genes of miR-671-3p were determined using the miRWalk 2.0 database (zmf.umm.uni-heidelberg.de/apps/zmf/mirwalk2), which contains 12 online tools, namely Targetscan, RNAhybrid, RNA22, PITA, Pictar2, miRWalk, Microt4, miRNAMap, miRDB, mirbridge, miRanda and miRMap. Targets predicted by >3 algorithms were selected for GO functional annotation and KEGG pathway analyses using th […]


Fishing Into the MicroRNA Transcriptome

Front Genet
PMCID: 5868305
PMID: 29616080
DOI: 10.3389/fgene.2018.00088

[…] ature, researchers often look up for which tool or combination of tools allows for the best quality results. Oliveira et al. () shows that the union of the results provided by TargetScan, miRanda and RNA22 provide a better performance (balance of sensitivity and specificity) than any of these tools alone or other combination of them. However, it is important to keep in mind that any target predict […]


Resveratrol Improves Endothelial Progenitor Cell Function through miR 138 by Targeting Focal Adhesion Kinase (FAK) and Promotes Thrombus Resolution In Vivo

PMCID: 5822936
PMID: 29447140
DOI: 10.12659/MSM.906116

[…] of FAK. After transfected with FAK siRNA, RSV-induced EPCs exhibited decreased cell migration and angiogenesis when compared to the vehicle controls group ().Based on multiple databases (TargetScan, RNA22-HAS and MicroCosm Targets), FAK has been regarded as a potential target of miR-138 because of the presence of potential binding site located at 3′ UTR. To confirm that FAK is directly regulated […]


Long Non coding MIR205HG Depletes Hsa miR 590 3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma

PMCID: 5858504
PMID: 29556360
DOI: 10.7150/thno.22167

[…] dated targets of miR-590-3p. Furthermore, we searched for their "seed sequence" on CCNB1 and Cdk1 mRNA using MiRTarbase, as shown in Figure A . We confirmed this analysis also using MicroRNA.org and rna22 packages . […]


MicroRNA 27a 5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis

PMCID: 5833437
PMID: 29415999
DOI: 10.1038/s41419-017-0241-y

[…] d the number of transcription factor binding sites was retrieved with the help of ConSite web-based tool, after the alignment between miRNA promoter sequence and c-Myc-binding sequence. Additionally, RNA22 tool was used to predict miRNA target sites in the mRNA sequence of EGFR, Akt1, and mTOR. […]


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RNA22 institution(s)
Computational Medicine Center, Thomas Jefferson University, Philadelphia, PA, USA
RNA22 funding source(s)
Supported by a William M. Keck Foundation grant award and Thomas Jefferson University.

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