Offers an approach dedicated to the determination of temperature B-factor. RNAflex supplies a web platform that is a based only on RNA sequence information and combines support vector machine (SVM) models and sequence profiles. The method was tested on a dataset of 142 RNA structures. It generates a Pearson’s correlation coefficient (PCC) of 0.51 for the fivefold cross validation.
School of Information and Communication Technology and Institute for Glycomics, Griffith University, Brisbane, QLD, Australia; School of Data and Computer Science, Sun Yat-sen University, Guangzhou, China
RNAflex funding source(s)
Supported by the National Health and Medical Research Council (Australia): 1059775 and 1083450; the Australian Research Council’s Linkage Infrastructure, Equipment and Facilities funding scheme (project number LE150100161); the National Natural Science Foundation of China: 61772566 and U1611261.