RNAmutants specifications


Unique identifier OMICS_07479
Name RNAmutants
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publications for RNAmutants

RNAmutants in publications

PMCID: 5068708
PMID: 27755571
DOI: 10.1371/journal.pone.0164726

[…] identifying biological rnas with topologically similar structures. a coarse-grained rna secondary structure representation has also been used to predict rna deleterious mutations by rnamute [] and rnamutants []. in addition, a coarse-grained approach is also applied for rna design such as rnaexinv [] and nanofolder []. we demonstrate the utility of the xios approach by classifying […]

PMCID: 4333902
PMID: 25649229
DOI: 10.1186/s12864-014-1203-8

[…] differ by exactly one point mutation (1-mutant neighbors) []. there are a variety of existing computational methods [] and programs designed to evaluate rna robustness (e.g. rnamute, rdmas, rsre, rnamutants, snpfold, rnasnp, remurna, and rchange) [,,-]. all of these approaches focus on a single input sequence and the ability of its neighboring mutants to maintain a “wild-type” structure. […]

PMCID: 3526635
PMID: 23284639
DOI: 10.1371/journal.pone.0050506

[…] we see how to use fftbor to sample structures from the boltzmann ensemble of structures having base pair distance from ., in , , we introduced the a related parametric rna structure algorithm, rnamutants, which computes the partition function and minimum free energy structure over all secondary structures of all -point mutants of a given rna sequence . in , rnamutants was extended […]

PMCID: 3463434
PMID: 22958879
DOI: 10.1186/1748-7188-7-24

[…] general, neither the original rnamute [] nor rdmas [] can handle multiple-point mutations. consequently, rnamute [] was extended to multirnamute [] and based on the approach of [], the web servers rnamutants [] and later corrna [] were developed. a web server for multirnamute was worked out in []. there is, however, one common feature that should be taken into account when considering […]

PMCID: 3303743
PMID: 22759654
DOI: 10.1186/1471-2164-13-S4-S6

[…] we used to generate the predictions are also indicated in figure . it should also be noted that all of these programs are designed to predict the best secondary structure, and with the exception of rnamutants are not necessarily optimized for identifying the mutation that most disrupts rna structure., we aim to use rna structure prediction programs to predict the esdc values determined […]

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RNAmutants institution(s)
Department of Mathematics, MIT, Cambridge, MA, USA

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