RotaC statistics

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Citations per year

Number of citations per year for the bioinformatics software tool RotaC

Tool usage distribution map

This map represents all the scientific publications referring to RotaC per scientific context
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Associated diseases

This word cloud represents RotaC usage per disease context

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RotaC specifications


Unique identifier OMICS_22641
Name RotaC
Interface Web user interface
Restrictions to use Academic or non-commercial use
Programming languages Java, Perl, PHP
Computer skills Basic
Version 1.0
Maintained Yes


  • person_outline Piet Maes
  • person_outline Jelle Matthijnssens
  • person_outline Mustafizur Rahman
  • person_outline Marc Van Ranst

Publication for RotaC

RotaC citations


Viromic Analysis of Wastewater Input to a River Catchment Reveals a Diverse Assemblage of RNA Viruses

PMCID: 5964442
DOI: 10.1128/mSystems.00025-18

[…] the number of rotavirus types present in this sample. Given the amino acid similarities with both RVA and RVC types, we suggest there are at least two and possibly three types present here.Using the RotaC 2.0 typing tool for RVA and Blast-based similarity to known genotypes, we have typed the rotavirus genome segments found here (). The combined genomic makeup of the RV community in sample LI_13- […]


Emergence of Human G2P[4] Rotaviruses in the Post vaccination Era in South South Korea: Footprints of Multiple Interspecies Re assortment Events

Sci Rep
PMCID: 5902508
PMID: 29662148
DOI: 10.1038/s41598-018-24511-y
call_split See protocol

[…] uences were assembled using BioEdit software ( Genotype assignment for each gene was performed using BLAST ( and RotaC 2.0 ( […]


Analysis of structure function relationship in porcine rotavirus A enterotoxin gene

PMCID: 5799398
PMID: 28057906
DOI: 10.4142/jvs.2018.19.1.35

[…] um likelihood statistical method was applied to construct a phylogenetic tree with the selected model. Tree robustness was tested by using the bootstrap method based on 1,000 replicates. Further, the RotaC2.0 web-based tool for classification of RVA was used to determine the genotype of the NSP4 sequences []. To elucidate the genetic diversity among nsp4 genes, a haplotype network was inferred by […]


Emergence of Double and Triple Gene Reassortant G1P[8] Rotaviruses Possessing a DS 1 Like Backbone after Rotavirus Vaccine Introduction in Malawi

J Virol
PMCID: 5774894
PMID: 29142125
DOI: 10.1128/JVI.01246-17

[…] strains by using both de novo and reference DNA sequence assembler algorithms implemented in Geneious software v8 (). Rotavirus genotypes were assigned to each of the 11 genome segments by using the RotaC v2.0 Web-based automated rotavirus genotyping tool ( (). […]


Faecal shedding of rotavirus vaccine in Chinese children after vaccination with Lanzhou lamb rotavirus vaccine

Sci Rep
PMCID: 5772666
PMID: 29343800
DOI: 10.1038/s41598-018-19469-w
call_split See protocol

[…] s from samples with the highest viral loads were amplified and sequenced. All primers used are listed in Supplementary TableĀ . Virus genotype and nucleotide sequence similarities were analysed by the RotaC v2.0 ( automated genotyping tool and BLASTn ( […]


Analysis of NSP4 Gene and Its Association with Genotyping of Rotavirus Group A in Stool Samples

PMCID: 5712384
PMID: 28693095
DOI: 10.22034/ibj.22.1.42

[…] mples may be significant.However, RV genome is segmented, and evolution of each segment can be analyzed for G or P typing[,]. As a result, genotyping of NSP4 gene in the samples was carried out using RotaC2.0 web server, and E1 and E2 genotypes were identified. From 27 sequences samples, E1 (20 cases, ~77%) and E2 (6 cases, ~23%) were obtained. In general, E1 and E2 genotypes are dominant E genoty […]

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RotaC institution(s)
Clinical Virology, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium
RotaC funding source(s)
Supported by a postdoctoral grant from the 'Fonds voor Wetenschappelijk Onderzoek (FWO)-Vlaanderen'; by the Institute for the Promotion and Innovation through Science and Technology in Flanders (IWT Vlaanderen).

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