An integrated resource for post-translational modifications (PTMs), providing not only a comprehensive dataset of experimentally verified PTMs that are supported by the literature but also an integrative platform for accessing all available databases and tools that are associated with PTM analysis. In addition to collecting experimental PTM data from public databases, this update manually curates more than 12 000 PTM peptides, including the emerging S-nitrosylation, S-glutathionylation and succinylation, from approximately 500 research articles which were extracted by text mining. This update develops an integrative platform for PTM analyses by integrating all available databases and tools that are associated with over 20 PTM types.
A database that integrates the experimentally verified cysteine S-Nitrosylation sites from multiple species. Users are allowed to search a group of interested proteins/genes and the system reconstructs the SNO regulatory network based on the information of metabolic pathways and protein-protein interactions.
Gathers literature about single-target S-nitrosation and S-nitrosoproteomic research from PubMed. SNObase is a manually curated database that collects information about S-nitrosation target, site, biological model, related disease, trends of S-nitrosation level and manner of regulation in protein function. Searches can be made by several queries as well as description, gene symbol, SNObase ID or Related pathophysiological process.