Tool stats & trends
Looking to identify usage trends or leading experts?
|Alternative name||Structural antibody database|
|Restrictions to use||None|
Publication for Structural antibody database
Repertoire Analysis of Antibody CDR H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification
[…] e actual antibody structure. Thus, we applied FIRST-PG analysis to a large set of antibody crystal structures. We curated the set of all non-redundant mouse and human antibody crystal structures from SAbDab (). To be consistent with the models produced by RosettaAntibody, we truncated the structure of each antibody to only the Fv domain, excluding other antibody regions or antigen. Then, we used I […]
Antibody H3 Structure Prediction
[…] Sphinx is a recently-developed method that integrates knowledge-based and ab initio approaches . An H3-specific version is freely available for use at opig.stats.ox.ac.uk/webapps/sabdab-sabpred/SphinxH3.php. The algorithm starts with a database search; loop fragments that are shorter than the target loop are extracted based on their sequence similarity to the target. The struc […]
Examining Variable Domain Orientations in Antigen Receptors Gives Insight into TCR Like Antibody Design
[…] The orientations of each of the TCR-like antibodies found in SAbDab were calculated using the ABangle methodology. Supplementary Figure S2 in shows where each of these lie compared to the background antibody distribution. There appears to be no preference for […]
Looking to check out a full list of citations?
Be the first to review SAbDab