SAbDab statistics

Tool stats & trends

Looking to identify usage trends or leading experts?

SAbDab specifications

Information


Unique identifier OMICS_03062
Name SAbDab
Alternative name Structural antibody database
Restrictions to use None
Maintained No

Publication for Structural antibody database

SAbDab citations

 (3)
library_books

Repertoire Analysis of Antibody CDR H3 Loops Suggests Affinity Maturation Does Not Typically Result in Rigidification

2018
Front Immunol
PMCID: 5840193
PMID: 29545810
DOI: 10.3389/fimmu.2018.00413

[…] e actual antibody structure. Thus, we applied FIRST-PG analysis to a large set of antibody crystal structures. We curated the set of all non-redundant mouse and human antibody crystal structures from SAbDab (). To be consistent with the models produced by RosettaAntibody, we truncated the structure of each antibody to only the Fv domain, excluding other antibody regions or antigen. Then, we used I […]

library_books

Antibody H3 Structure Prediction

2017
Comput Struct Biotechnol J
PMCID: 5312500
PMID: 28228926
DOI: 10.1016/j.csbj.2017.01.010

[…] Sphinx is a recently-developed method that integrates knowledge-based and ab initio approaches . An H3-specific version is freely available for use at opig.stats.ox.ac.uk/webapps/sabdab-sabpred/SphinxH3.php. The algorithm starts with a database search; loop fragments that are shorter than the target loop are extracted based on their sequence similarity to the target. The struc […]

library_books

Examining Variable Domain Orientations in Antigen Receptors Gives Insight into TCR Like Antibody Design

2014
PLoS Comput Biol
PMCID: 4168974
PMID: 25233457
DOI: 10.1371/journal.pcbi.1003852

[…] The orientations of each of the TCR-like antibodies found in SAbDab were calculated using the ABangle methodology. Supplementary Figure S2 in shows where each of these lie compared to the background antibody distribution. There appears to be no preference for […]

Citations

Looking to check out a full list of citations?

SAbDab institution(s)
Department of Statistics, University of Oxford, Oxford, UK; Informatics, UCB Pharma, Slough, UK; Roche Pharma Research and Early Development, Chinahe Diagnostics GmbH, Penzberg, Germany

SAbDab reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review SAbDab