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Associated diseases

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SAPTA specifications

Information


Unique identifier OMICS_10624
Name SAPTA
Alternative name Scoring Algorithm for Predicting TALEN Activity
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Gang Bao <>

Publication for Scoring Algorithm for Predicting TALEN Activity

SAPTA in publications

 (16)
PMCID: 5511212
PMID: 28710417
DOI: 10.1038/s41598-017-05696-0

[…] activity. the second criterion is to screen for unique areas in the genome in order to minimize off-target effects. taken these criteria into consideration, talen pairs were screened using sapta software and the region selected was such way that it targeted at position 44 which was in the start region of exon i of e7 (fig. ). this talen pair had 19 binding sites on either side […]

PMCID: 4837413
PMID: 27095599
DOI: 10.1038/srep24652

[…] needed for golden gate construction, and 1 day longer than tale toolbox method., talens, talen9m10-3l and -r, targeting the first exon of cyp9m10 in jpp (genbank id: ab332027) were designed with the sapta algorithm and constructed using the pc assembly described above. frame-shifting in this exon was expected to disrupt the gene function because critical protein domains such as a heme-binding […]

PMCID: 5198827
PMID: 28053888
DOI: 10.1016/j.jtcme.2016.02.002

[…] tridoshas of the human body should be maintained for a healthy state of living by following the principles of divine wisdom. the body is believed to be composed of seven types of tissues called as “sapta dhatus”. these seven tissues work in coordination with each for proper physiological functioning of the human body. the rakta dhatu resembles the blood and regulates the circulation of blood […]

PMCID: 4786925
PMID: 26750397
DOI: 10.1038/mt.2016.1

[…] of talen pairs. the e-talen webtool incorporates a scoring algorithm for ranking potential talens, but this scoring system was not experimentally validated. the second-generation talen design tool sapta (scoring algorithm for predicting talen activity) uses improved guidelines for talen design based on rules derived from experimentally testing 205 individual talen monomers. the sapta algorithm […]

PMCID: 4715443
PMID: 26788434
DOI: 10.7717/peerj.1563

[…] as one of the most endangered of all cetaceans in the world and the second scarcest freshwater cetacean. the population is estimated to be less than 2,000 individuals. in nepal’s narayani, sapta koshi, and karnali river systems, survival of grd continues to be threatened by various anthropogenic activities, such as dam construction and interactions with artisanal fisheries. a basic […]


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SAPTA institution(s)
Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA
SAPTA funding source(s)
National Institutes of Health (NIH Nanomedicine Development Center Award, PN2EY018244); National Science Foundation Graduate Research Fellowship (DGE-1148903)

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