SCALOP specifications

Information


Unique identifier OMICS_32532
Name SCALOP
Alternative name Sequence-based antibody CAnonical LOoP structure annotation
Software type Application/Script
Interface Command line interface
Restrictions to use None
Input data A set of amino acid sequences of full antibody chains.
Input format FASTA
Operating system Unix/Linux, Mac OS
Programming languages Python
Computer skills Advanced
Stability Stable
Requirements
HMMER
Registration required Yes
Maintained No

Versioning


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Maintainer


This tool is not available anymore.

Information


Unique identifier OMICS_32532
Name SCALOP
Alternative name Sequence-based antibody CAnonical LOoP structure annotation
Interface Web user interface
Restrictions to use None
Input data A set of amino acid sequences of full antibody chains.
Input format FASTA
Programming languages Python
Computer skills Basic
Stability Stable
Maintained No

Maintainer


This tool is not available anymore.

Publication for Sequence-based antibody CAnonical LOoP structure annotation

SCALOP institution(s)
Department of Statistics, University of Oxford, Oxford, UK; Roche Pharma Research and Early Development, Large Molecule Research, Roche Innovation Center Munich, Penzberg, Germany; UCB Pharma, Slough, UK; Computational and Modelling Sciences, GlaxoSmithKline Research and Development, Stevenage, UK; Antibody Discovery and Protein Engineering, MedImmune, Cambridge, UK
SCALOP funding source(s)
Supported by funding from the EPSRC and MRC [grant number EP/L016044/1].

SCALOP review

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KUNKUN

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Desktop
The cluster information in the output is not very useful in antibody CDR template selection for modelling. This tool is suitable for High-throughput sequence analysis.