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Scansite specifications


Unique identifier OMICS_02980
Name Scansite
Interface Web user interface
Restrictions to use None
Programming languages Java
Computer skills Basic
Version 3.0
Stability Beta
Maintained Yes


  • person_outline Michael B. Yaffe

Publications for Scansite

Scansite citations


Non canonical activation of DAPK2 by AMPK constitutes a new pathway linking metabolic stress to autophagy

Nat Commun
PMCID: 5931534
PMID: 29717115
DOI: 10.1038/s41467-018-03907-4

[…] To search for possible kinases that regulate DAPK2, the amino acid sequence of DAPK2 was analyzed using the Scansite algorithm at high stringency, looking for all potential motifs. Four potential phosphorylation sites were found (Tyr208, Thr265, Ser289, Thr359). Next, this list was crossed with the PhosphoS […]


SRARP and HSPB7 are epigenetically regulated gene pairs that function as tumor suppressors and predict clinical outcome in malignancies

Mol Oncol
PMCID: 5928383
PMID: 29577611
DOI: 10.1002/1878-0261.12195

[…] scansite 3 software was employed to identify motifs within HSPB7 protein that are likely to be phosphorylated by specific protein kinases or bind to domains such as SH2, 14‐3‐3, or PDZ (http://scansit […]


Acquired Enamel Pellicle Engineered Peptides: Effects on Hydroxyapatite Crystal Growth

Sci Rep
PMCID: 5830524
PMID: 29491390
DOI: 10.1038/s41598-018-21854-4

[…] e at a particular pH by using user-specified pK values, and this calculation is repeated until the pH corresponding to a net charge of zero is attained. The pI values quoted were calculated using the Scansite option at pH 6.8. […]


Phosphorylation of CDC25C by AMP activated protein kinase mediates a metabolic checkpoint during cell cycle G2/M phase transition

PMCID: 5892595
PMID: 29467227
DOI: 10.1074/jbc.RA117.001379

[…] osphorylating and modulating any of the above mitotic regulators. Previous studies have revealed the optimal consensus phosphorylation motif for AMPK (, ). We therefore applied a bioinformatics tool (Scansite3 ()) to search for putative AMPK-mediated phosphorylation motifs in CDC25C, WEE1, MYT1, CDC2, and cyclin B1. The inspection of these protein sequences revealed one putative AMPK phosphorylati […]


Astragaloside IV Inhibits Adipose Lipolysis and Reduces Hepatic Glucose Production via Akt Dependent PDE3B Expression in HFD Fed Mice

Front Physiol
PMCID: 5787100
PMID: 29410630
DOI: 10.3389/fphys.2018.00015

[…] orylation in the early period and reached the highest expression at 4 h (Figure ). To identify whether PDE3B could be phosphorylated by Akt, complete amino-acid sequences of PDE3B were scanned by the Scansite databases. Search result revealed that mice PDE3B contains Akt consensus phosphorylation sites (Figure ), suggesting that the involvement of Akt in PDE3B phosphorylation. Then immunoprecipita […]


Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG I signalosome

PLoS Pathog
PMCID: 5794190
PMID: 29357390
DOI: 10.1371/journal.ppat.1006852

[…] ases including Gene Ontology [], Panther [] and the Kyoto Encyclopedia of Genes and Genomes (KEGG) []. Protein interaction networks were visualized using the CIRCOS software []. The 14-3-3Pred [] and Scansite Motifscan [] softwares were used to predict putative 14-3-3 binding site in BPLF1. […]


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Scansite institution(s)
Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA

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