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SCide specifications

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Unique identifier OMICS_07144
Name SCide
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability No
Maintained No

Publication for SCide

SCide citations

 (9)
library_books

In silico Mapping of Protein Unfolding Mutations for Inherited Disease

2016
Sci Rep
PMCID: 5131339
PMID: 27905547
DOI: 10.1038/srep37298

[…] performance of computational protein stability predictors. here, the performance of 11 online stability predictors was analyzed: cupsat, dmutant, foldx, i-mutant2.0, i-mutant3.0, multimutate, mupro, scide, scpred, and sride. in total, 1,784 missense mutations in 80 different proteins were analyzed. the mutations were categorized as stabilizing, neutral, or destabilizing. the programs all predict […]

library_books

Function annotation of peptides generated from the non coding regions of D. melanogaster genome

2016
Bioinformation
PMCID: 5267965
PMID: 28149056
DOI: 10.6026/97320630012202

[…] for evaluating the peptide structures based on the intra-molecular interactions and the same was adopted for the study. the stability centres (scs) of the protein/peptide were predicted using the scide program []. the stability centres are residues that are involved in cooperative long-range contacts, which are important in maintaining the stability of the protein. the total energy […]

library_books

Characterization of a thermostable endoglucanase produced by Isoptericola variabilis sp. IDAH9

2015
PMCID: 4704623
PMID: 26691485
DOI: 10.1590/S1517-838246420140846

[…] of mesophilic cellulomonas flavigena lost its activity when it was incubated at 70 °c for 30 min ()., for the determination of stabilizing regions, the predicted structure () was further analyzed by scide web-based algorithm (). the results of the analysis are depicted in . this indicates that the stabilizing residues are mainly localized at 200 to 260 and 300 to 350. also, there are stabilizing […]

library_books

Computational and Experimental Approaches to Reveal the Effects of Single Nucleotide Polymorphisms with Respect to Disease Diagnostics

2014
Int J Mol Sci
PMCID: 4100115
PMID: 24886813
DOI: 10.3390/ijms15069670

[…] to decipher the stability changes due to mutations. namely, these servers are eslpred [], svmprot [], svmprat [,], automute [,], fish [,], ond-crf [], prosms, protsrf, iptree-stab [], mupro, scide [,], scpred [], mustab [,], popmusic, pmut [,,], snap [], snps and gene ontology (snps&go) [], parepro [], canpredict [], nssnpanalyzer [,,], mutpred [], hansa [,], mutation taster [] […]

library_books

The role of CDK5 and GSK3B kinases in hyperphosphorylation of microtubule associated protein tau (MAPT) in Alzheimer's disease

2013
Bioinformation
PMCID: 3910359
PMID: 24497730
DOI: 10.6026/97320630091023

[…] based tool for the prediction of atp binding residue in a protein sequence. in addition stabilization potential of the complex structure is computed by two programs namely stabilization center (scide) [] and stabilization residue (sride) []. scide program predicts the number of residues which acts as stabilization center in the complex as well as in the individual molecule. […]

library_books

An association adjusted consensus deleterious scheme to classify homozygous Mis sense mutations for personal genome interpretation

2013
BioData Min
PMCID: 3892026
PMID: 24365473
DOI: 10.1186/1756-0381-6-24

[…] of amino acids with specialized roles regarding protein stability, namely long-range stabilization center (sc) residues and stabilizing residues (srs). these residues were inferred from the scide [,] and sride webservers [], respectively. ligand binding residues for each protein were retrieved from pdbe (http://www.ebi.ac.uk/pdbe/) or were predicted using 3dligandsite []. amino acid […]


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SCide institution(s)
Institute of Enzymology Biological Research Center, Hungarian Academy of Sciences, Budapest, Hungary

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