Finds cancer subtypes. Scluster is based on an adaptive sparse reduced-rank regression (S-rrr) method. It builds a fused patient-by-patient network and then applies a spectral clustering method for the identification of cancer subtypes. This tool can deal with high dimensional statistical data under the Gaussian variable model. It recognizes the principal low-dimension subspace and can be run without data preprocessing step.
College of Electrical Engineering and Automation, Anhui University, Hefei, China; Institute of Health Sciences, Anhui University, Hefei, China; Co-Innovation Center for Information Support and Assurance Technology, Anhui University, Hefei, China
Scluster funding source(s)
Supported by the National Natural Science Foundation of China (31301101&61272339), the Anhui Provincial Natural Science Foundation (1408085QF106&1508085QF135).