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SCoPE-MS specifications


Unique identifier OMICS_32591
Alternative name Single Cell ProtEomics by Mass Spectrometry
Software type Application/Script
Interface Command line interface
Restrictions to use Academic or non-commercial use
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


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  • person_outline Bogdan Budnik
  • person_outline Nikolai Slavov

Publication for Single Cell ProtEomics by Mass Spectrometry

SCoPE-MS citations


Partitioning the metabolic scope: the importance of anaerobic metabolism and implications for the oxygen and capacity limited thermal tolerance (OCLTT) hypothesis

PMCID: 4896295
PMID: 27293766
DOI: 10.1093/conphys/cow019

[…] ncreased the interest in developing predictive models for effects of climate change on different species (; ). The oxygen- and capacity-limited thermal tolerance (OCLTT) hypothesis uses the metabolic scope (MS) to derive a range of tolerable temperatures (thermal window) of organisms with an optimal temperature for oxygen supply to sustain life, including growth, foraging, migration and reproducti […]


Detection of hydrogen peroxide in Photosystem II (PSII) using catalytic amperometric biosensor

Front Plant Sci
PMCID: 4606053
PMID: 26528319
DOI: 10.3389/fpls.2015.00862

[…] rimental conditions are as follows: PSII membranes (150 μg Chl ml−1); EMPO, 25 mM; phosphate buffer, 40 mM (pH 6.5), DCMU, 20 μM and desferal, 50 μM. Spectra were recorded using EPR spectrometer Mini Scope MS400 (Magnettech GmbH, Berlin, Germany) with EPR conditions as follows: microwave power, 10 mW; modulation amplitude, 1 G; modulation frequency, 100 kHz; sweep width, 100 G; scan rate, 1.62 G s […]


Intraspecific variation in aerobic and anaerobic locomotion: gilthead sea bream (Sparus aurata) and Trinidadian guppy (Poecilia reticulata) do not exhibit a trade off between maximum sustained swimming speed and minimum cost of transport

Front Physiol
PMCID: 4330683
PMID: 25741285
DOI: 10.3389/fphys.2015.00043

[…] are additional to standard metabolism. These demands are met within the range set by the maximum metabolic rate (MO2max) (Priede, ). The difference between MO2stand and MO2max is termed the metabolic scope (MS). Because MS is strongly influenced by environmental variables, including temperature and oxygen availability, MS is predicted to be a major physiological variable in relation to climate cha […]


Predicting future thermal habitat suitability of competing native and invasive fish species: from metabolic scope to oceanographic modelling

PMCID: 4778460
PMID: 27293680
DOI: 10.1093/conphys/cou059

[…] ensively and cause large-scale impact on natural habitats and local food chains (; ).Here, we aim to estimate how changes in water temperature influence the physiological performances (i.e. metabolic scope, MS) of both marbled spinefoot and salema. Metabolic scope represents the scope within which aerobic activities, such as swimming, feeding or growth, must be accommodated (). As such, MS is a su […]


Evidence for the Involvement of Loosely Bound Plastosemiquinones in Superoxide Anion Radical Production in Photosystem II

PLoS One
PMCID: 4277363
PMID: 25541694
DOI: 10.1371/journal.pone.0115466

[…] 6.5). PSII membranes were illuminated using a halogen lamp with a light guide (Schott KL 1500, Schott AG, Mainz, Germany) at room temperature. The spectra were recorded using an EPR spectrometer Mini Scope MS400 (Magnettech GmbH, Germany). The following EPR conditions were used: microwave power, 10 mW; modulation amplitude, 1 G; modulation frequency, 100 kHz; sweep width, 100 G; and scan rate, 1.6 […]


Schooling Increases Risk Exposure for Fish Navigating Past Artificial Barriers

PLoS One
PMCID: 4182462
PMID: 25268736
DOI: 10.1371/journal.pone.0108220

[…] r flow avoidance or vortex capturing than from channeling effects between parallel swimmers.Recent evidence has shown that leader positions are significantly correlated with an individual's metabolic scope (MS), with spatial positioning from a school's front to rear being negatively correlated with the constituents' MS . Individual fish have also been shown to display less muscle activity when dra […]

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SCoPE-MS institution(s)
MSPRL, FAS Division of Science, Harvard University, Cambridge, MA, USA; Department of Biology, Northeastern University, Boston, MA, USA; Department of Bioengineering, Northeastern University, Boston, MA, USA
SCoPE-MS funding source(s)
Supported by startup funds from Northeastern University and a New Innovator Award from the NIGMS from the National Institutes of Health under Award Number DP2GM123497.

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