Main logo
?
tutorial arrow
×
Create your own tool library
Bookmark tools and put favorites into folders to find them easily.

Screening for Non-Acceptable Polymorphisms SNAP

A neural-network based tool to be used for the evaluation of functional effects single amino acid substitutions in proteins. SNAP utilizes various biophysical characteristics of the substitution, as well as evolutionary information, some predicted—or when made available observed—structural features, and possibly annotations, to predict whether or not a mutation is likely to alter protein function (in either direction: gain or loss). SNAP identifies over 80% of the non-neutral mutations at 77% accuracy and over 76% of the neutral mutations at 80% accuracy at its default threshold.

User report

tutorial arrow
×
Vote up tools and offer feedback
Give value to tools and make your expertise visible
Give your feedback on this tool
Sign up for free to join and share with the community

0 user reviews

0 user reviews

No review has been posted.

SNAP forum

tutorial arrow
×
Communicate with other users
Participate in the forum to get support for using tools. Ask questions about technical specifications.
Take part in the discussion
Sign up for free to ask question and share your advices

No open topic.

SNAP classification

SNAP specifications

Interface:
Web user interface
Input data:
A protein sequence
Computer skills:
Basic
Stability:
Stable
Restrictions to use:
None
Input format:
FASTA
Version:
2.0
Maintained:
Yes

Credits

tutorial arrow
×
Promote your skills
Define all the tasks you managed and assign your profile the appropriate badges. Become an active member.
Promote your work
Sign up for free to badge your contributorship

Publications

Institution(s)

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA

Link to literature

By using OMICtools you acknowledge that you have read and accepted the terms of the end user license agreement.