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Unique identifier OMICS_12401
Name SDAP
Alternative name Structural Database of Allergenic Proteins
Restrictions to use Academic or non-commercial use
Database management system MySQL, Oracle
Community driven No
Data access Browse
User data submission Allowed
Maintained Yes

Maintainer


  • person_outline Werner Braun

Publication for Structural Database of Allergenic Proteins

SDAP citations

 (15)
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Proteomic Analysis and Identification of Possible Allergenic Proteins in Mature Pollen of Populus tomentosa

2018
Int J Mol Sci
PMCID: 5796197
PMID: 29337913
DOI: 10.3390/ijms19010250
call_split See protocol

[…] he identified proteins were categorized by function according to data from Blast2GO []. The output GO terms were then slimmed in REVIGO and treemaps were produced []. Allergen was predicted using the SDAP [] on the base of sequence similarity (>35%) between presently obtained proteins and reported allergen proteins and the presence of consecutive amino acids (at least eight) in the analyzed protei […]

library_books

A novel B and helper T cell epitopes based prophylactic vaccine against Echinococcus granulosus

2017
PMCID: 5915707
PMID: 29713601
DOI: 10.15171/bi.2018.06

[…] , the prediction score of SVMc method based on amino acid composition (threshold= -0.4) and dipeptide composition (threshold= -0.2) was found to be about -0.696 and -0.419, respectively. Based on the SDAP prediction algorithm, the similarities (%) between Eg14-3-3 sequence and the most similar templates were ranged from 5.67 to 12.96, which are less than the threshold (35%). Moreover, in these ali […]

library_books

An Introduction to B Cell Epitope Mapping and In Silico Epitope Prediction

2016
J Immunol Res
PMCID: 5227168
PMID: 28127568
DOI: 10.1155/2016/6760830

[…] of novel and better algorithms for prediction. The B-cell epitope databases can be classified as multifaceted database such as IEDB and AntiJen, B-cell oriented database such as BciPep, Epitome, and SDAP, and single pathogenic organism oriented database such as the HIV Molecular Immunology Database, FLAVIdB, and Influenza Sequence and Epitope Database. It has to be mentioned that most of the avai […]

library_books

Structure of mammalian respiratory complex I

2016
Nature
PMCID: 5027920
PMID: 27509854
DOI: 10.1038/nature19095

[…] nd more complete models to be built for all 45 subunits (see below). Note that the former subunit MLRQ (NDUFA4) is no longer considered a subunit of complex I and that there are two copies of subunit SDAP. The only substantial unmodelled protein densities are underneath the tip of the membrane domain and are accounted for by the termini of two supernumerary subunits (B18 and ASHI).In well-resolved […]

library_books

In Silico Design of a Chimeric Protein Containing Antigenic Fragments of Helicobacter pylori; A Bioinformatic Approach

2016
PMCID: 4899534
PMID: 27335622
DOI: 10.2174/1874285801610010097

[…] AlgPred tool was used to plot IgE epitopes of the sequence. There was no allergenicity found by MAST results. Based on various prediction approaches in the AlgPred tool and SDAP allergen library, this protein would not have any allergenicity and also not show significant similarities between any of the regions. As a final point, based on obtaining data from APPEL predict […]

library_books

A novel lipid transfer protein from the pea Pisum sativum: isolation, recombinant expression, solution structure, antifungal activity, lipid binding, and allergenic properties

2016
BMC Plant Biol
PMCID: 4852415
PMID: 27137920
DOI: 10.1186/s12870-016-0792-6

[…] d for Len c 3, Pha v 3, Ara h 9, and Pru p 3 (32, 20, 17, and 16 matches, respectively). Presumable allergenic properties were also confirmed by using other web tools, such as AllergenFP, AlgPred and SDAP.Three sequential IgE epitopes were previously characterized in Pru p 3 (see Fig. ) []. Two of them form conformational epitope (Asn35-Ala46/Ser76-Tyr79) which includes three key amino acid residu […]

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SDAP institution(s)
Sealy Center for Structural Biology, Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston, TX, USA
SDAP funding source(s)
The SDAP project is supported by grants from the National Institute of Health (2R56AI064913), and the U.S. Environmental Protection Agency under a STAR Research Assistance Agreement (No. RD 834823).

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