SeqEM specifications

Information


Unique identifier OMICS_00074
Name SeqEM
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Version 1.0
Stability Stable
Maintained Yes

Versioning


No version available

Maintainers


  • person_outline Eden Martin
  • person_outline SeqEM Team

Publication for SeqEM

SeqEM citation

library_books

Variant Callers for Next Generation Sequencing Data: A Comparison Study

2013
PLoS One
PMCID: 3785481
PMID: 24086590
DOI: 10.1371/journal.pone.0075619

[…] cation. Early probabilistic methods, such as Mapping and Assembly with Quality (MAQ) [] and SOAPsnp [], used fixed prior values for heterozygote probabilities and nucleotide-read error probabilities. SeqEM [] introduces multiple-sample genotype calling via an adaptive approach employing the expectation-maximization (EM) algorithm to estimate the model parameters. Hardy-Weinberg equilibrium (HWE) c […]

SeqEM institution(s)
John P Hussman Institute for Human Genomics and the Dr John T Macdonald Foundation Department of Human Genetics, Miller School of Medicine, University of Miami, Miami, FL, USA
SeqEM funding source(s)
Supported by National Human Genome Research Institute (RC2HG005605), National Institute for Neurology and Stroke (U54NS065712 and R01NS026630).

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