SeqSIMLA pipeline

SeqSIMLA specifications

Information


Unique identifier OMICS_08584
Name SeqSIMLA
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages C++
License GNU General Public License version 2.0
Computer skills Advanced
Version 2.5
Stability Stable
Maintained Yes

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Publications for SeqSIMLA

SeqSIMLA IN pipelines

 (2)
2018
PMCID: 5766643
PMID: 29358944
DOI: 10.3389/fgene.2017.00228

[…] et al., 2005) to generate a population of 10,000 sequences (i.e., haplotypes) in two independent 30 kb regions based on a european ancestry. each region consisted of approximately 600 variants. seqsimla2 (chung et al., 2015) was then used to simulate case-control samples based on the 10,000 sequences. for type i error simulations, the penetrance function for seqsimla2 was specified as: […]

2018
PMCID: 5766643
PMID: 29358944
DOI: 10.3389/fgene.2017.00228

[…] of approximately 600 variants. seqsimla2 (chung et al., 2015) was then used to simulate case-control samples based on the 10,000 sequences. for type i error simulations, the penetrance function for seqsimla2 was specified as: (6)logit(p(affected))=α0 where α0 determined the baseline disease prevalence, which was assumed to be 5%. we considered four sets of sample sizes (i.e., 500 cases and 500 […]

SeqSIMLA institution(s)
Division of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli, Taiwan

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