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Sequence contamination identification software tools | Shotgun metagenomic sequencing data analysis

High-throughput sequencing technologies have strongly impacted microbiology, providing a rapid and cost-effective way of generating draft genomes and exploring microbial diversity. However, sequences obtained from impure nucleic acid preparations may contain DNA from sources other than the sample. Those sequence contaminations are a serious concern to the quality of the data used for downstream analysis, causing misassembly of sequence contigs and erroneous conclusions. Therefore, the removal of sequence contaminants is a necessary and required step for all sequencing projects.

Source text:
(Schmieder and Edwards, 2011) Fast identification and removal of sequence contamination from genomic and metagenomic datasets. PLoS One.

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