High-throughput sequencing data analysis bioinformatics software tools

High-throughput sequencing applications

Recent advances in the field of genomics have largely been due to the ability to sequence DNA at increasing throughput and decreasing cost. DNA sequencing was first introduced in 1977, and next-generation sequencing technologies have been available only during the past decade,…

High-throughput sequencing data analysis bioinformatics software tools

Most Recent Tools

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splitsource
Desktop

splitsource

Splits one or more sequences into original source sequences. splitsource…

Splits one or more sequences into original source sequences. splitsource processes the "source" features in the feature table. The "source" feature annotated the origin of a…

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seqcount
Desktop

seqcount

Reads and counts sequences. seqcount counts the frequency of occurrence of all…

Reads and counts sequences. seqcount counts the frequency of occurrence of all possible short sequences up to a user given maximum length in a set of sequence data and then writes this frequency…

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nthseq
Desktop

nthseq

Writes to file a single sequence from an input stream of sequences. nthseq…

Writes to file a single sequence from an input stream of sequences. nthseq allows to specify sequence by number, which is the order it appears in the input file. The user can specify the output file…

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showorf
Desktop

showorf

Displays a nucleotide sequence and translation in pretty format. showorf writes…

Displays a nucleotide sequence and translation in pretty format. showorf writes an input nucleotide sequence and its protein translation to an output file in a clear format that is suitable for…

Most Popular Tools

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SAMtools
Desktop

SAMtools

A suite of programs for interacting with high-throughput sequencing data. It…

A suite of programs for interacting with high-throughput sequencing data. It can manipulate alignments in the SAM/BAM/CRAM formats : reading, writing, editing, indexing, viewing and converting…

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Bowtie
Desktop

Bowtie

An ultrafast, memory-efficient short read aligner. It aligns short DNA…

An ultrafast, memory-efficient short read aligner. It aligns short DNA sequences (reads) to the human genome at a rate of over 25 million 35-bp reads per hour. Bowtie indexes the genome with a…

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SNPdryad
Web

SNPdryad

A computational method that can predict deleterious effect of amino acid…

A computational method that can predict deleterious effect of amino acid substitutions occurred in human proteins. SNPdryad outperforms other leading algorithms in accurately predicting deleterious…

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HOMER
Desktop

HOMER Hypergeometric Optimization of Motif EnRichment

A suite of tools for Motif Discovery and next-gen sequencing analysis. HOMER…

A suite of tools for Motif Discovery and next-gen sequencing analysis. HOMER contains many useful tools for analyzing ChIP-Seq, GRO-Seq, RNA-Seq, DNase-Seq, Hi-C and numerous other types of…

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