High-throughput sequencing data analysis bioinformatics software tools

High-throughput sequencing (HTS) or next-generation sequencing (NGS) technologies have revolutionized the biomedical research during the past decade. The ability to sequence multiple DNA molecules in parallel allows to produce quickly very large…

High-throughput sequencing applications

Most recent bioinformatics tools

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SeqDepot
Dataset

SeqDepot

Enables users to retrieve and process with minimal effort both primary and…

Enables users to retrieve and process with minimal effort both primary and intrinsic feature data for existing sequences. SeqDepot is a database that assimilates known primary sequences with…

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SEQWIKI
Dataset

SEQWIKI

Provides a structured catalogue of bioinformatics tools for high-throughput…

Provides a structured catalogue of bioinformatics tools for high-throughput sequencing (HTS) analysis. The content of SEQwiki falls into three categories: (i) software, (ii) service providers and…

seg-suite
Desktop

seg-suite

Contains a toolkit for arranging segments, alignments, and annotations of…

Contains a toolkit for arranging segments, alignments, and annotations of sequences. seg-suite performs composing alignments and is composed of a conversion program which transforms various formats…

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SPALN
Desktop
Web

SPALN

Allows users to map and align cDNA or protein sequences onto a whole genomic…

Allows users to map and align cDNA or protein sequences onto a whole genomic sequence (WGS). Spaln intends to improve automatic classification of alternative splicing and transcriptional initiation…

Most popular analytical software

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VENNY
Web

VENNY

An interactive tool for comparing lists with Venn Diagrams.

An interactive tool for comparing lists with Venn Diagrams.

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SAMtools
Desktop

SAMtools

A suite of programs for interacting with high-throughput sequencing data. It…

A suite of programs for interacting with high-throughput sequencing data. It can manipulate alignments in the SAM/BAM/CRAM formats : reading, writing, editing, indexing, viewing and converting…

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Bowtie
Desktop

Bowtie

A short read aligner that aligns short DNA sequences (reads) to the human…

A short read aligner that aligns short DNA sequences (reads) to the human genome at a rate of over 25 million 35-bp reads per hour. Bowtie indexes the genome with a Burrows-Wheeler index to keep its…

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SNPdryad
Web

SNPdryad

A computational method that can predict deleterious effect of amino acid…

A computational method that can predict deleterious effect of amino acid substitutions occurred in human proteins. SNPdryad outperforms other leading algorithms in accurately predicting deleterious…

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