Enables biology researchers to explore the entirety of very large microarray compendia in a biologically meaningful manner. SPELL is a scalable, context-specific search methodology implemented in an interactive, web-based search engine. The web-interface allows a researcher to provide a list of query genes, then the search engine reports which datasets are most relevant to that query, lists additional genes related to the query within the relevant conditions and displays the expression levels of these genes.
Lewis-Sigler Institute for Integrative Genomics, Princeton University, Carl Icahn Laboratory, Princeton, NJ, USA; Department of Computer Science, Princeton University, Princeton, NJ, USA
SPELL funding source(s)
Supported by NSF grant CNS-0406415, NSF CAREER award DBI-0546275, NIH grant R01 GM071966, NSF grant IIS-0513552, NIH grant T32 HG003284, NIGMS Center of Excellence grant P50 GM071508 and by a Google Research Award.