An integrated resource to analyze signaling pathway cross-talks, miRNAs and regulatory enzymes in zebrafish. SignaFish contains more than 200 curation-based signaling interactions, 132 further interactions listed in other resources, and it also lists potential miRNA-based regulatory connections for seven major signaling pathways. From the SignaFish website, users can reach other web resources, such as ZFIN. SignaFish provides signaling or signaling-related interactions that can be examined for each gene or downloaded for each signaling pathway. SignaFish serves as a navigating point for experimental design and evaluation for the zebrafish community and for researchers focusing on nonmodel fish species, such as cyclids.
Department of Genetics, Eötvös Loránd University, Budapest, Hungary; Max Delbrück Center for Molecular Medicine, Berlin, Germany; TGAC, The Genome Analysis Centre, Norwich, UK; European Molecular Biology Laboratory-European Bioinformatics Institute, Hinxton, UK; Wellcome Trust Genome Campus, Hinxton, UK; Department of Morphology and Physiology, Faculty of Health Sciences, Semmelweis University, Budapest, Hungary; Centre for Molecular Informatics, University of Cambridge, Cambridge, UK; Gut Health and Food Safety Programme, Institute of Food Research, Norwich Research Park, Norwich, UK; Department of Medical Chemistry, Semmelweis University, Budapest, Hungary; MTA-SE Lendület Nephrogenetic Laboratory, Budapest, Hungary