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Allows to conduct pathway analysis. sigPathway realizes analysis by calculating different statistics. It generates a list of potential pathways but interpreting that list itself can be time-consuming. The analysis may resemble the method of understanding the data in terms of modules. By examining the genes contained in each significant pathway, it should be possible to generate a network of interactions by groups of genes.

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sigPathway classification

sigPathway specifications

Software type:
Restrictions to use:
Programming languages:
Computer skills:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
GNU General Public License version 2.0

sigPathway distribution


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sigPathway support



  • Peter J. Park <>


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Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; Department of Neurology, Brigham and Women’s Hospital, Boston, MA, USA; Children’s Hospital Informatics Program, Boston, MA, USA; Bauer Center for Genomics Research, Harvard University, Cambridge, MA, USA; Molecular Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; Harvard-Partners Center for Genetics and Genomics, Boston, MA, USA

Funding source(s)

Supported by grants from the National Institute of General Medical Sciences; the Muscular Dystrophy Association and the National Institute of Neurological Disorders and Stroke; and Specialized Centers of Clinically Oriented Research in Pediatric Heart Development and Disease.

Link to literature

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