SimBoolNet statistics

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Associated diseases

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SimBoolNet specifications


Unique identifier OMICS_12459
Name SimBoolNet
Software type Framework/Library
Interface Graphical user interface
Restrictions to use None
Input format text
Operating system Unix/Linux, Mac OS, Windows
Programming languages Java
Computer skills Medium
Stability Stable
Maintained Yes



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  • person_outline Pawel F. Przytycki <>

Publication for SimBoolNet

SimBoolNet in publications

PMCID: 5072688
PMID: 27764199
DOI: 10.1371/journal.pone.0165049

[…] we first extracted a network (), which describes cell death regulation, from the model suggested by lee et al. []. in this network, cell death is enhanced by dna damage while inhibited by egfr. then simboolnet, an open source cytoscape plugin which had been designed for dynamically simulating the process of signal transduction based on an extended boolean network model [], was employed to run […]

PMCID: 4895646
PMID: 26818802
DOI: 10.1186/s12918-015-0249-9

[…] [, ]. however, odes-based models require a relatively detailed knowledge of kinetic parameters which is hardly available for all the pathways. previously, we proposed a simulation tool called simboolnet [] which is based on an extended boolean network model. although the performance of simboolnet in predicting protein activities was promising [], it has limited capability of dealing […]

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SimBoolNet institution(s)
National Center for Biotechnology Information, NLM/NIH, Bethesda, MD, USA; Department of Electrical & Computer Engineering, University of Maryland, College Park, MD, USA; Columbia University, Columbia College, New York, NY, USA; National Cancer Institute, NIH, Bethesda, MD, USA
SimBoolNet funding source(s)
Intramural Research Program of the National Institutes of Health (in part); National Library of Medicine (in part); National Cancer Institute, Center for Cancer Research (in part).

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