scDNA-seq analysis steps

Single-cell genomics aims to provide new perspectives to our understanding of genetics by bringing the study of genomes to the cellular level. These tools are opening up new frontiers by dissecting the contributions of individual cells to the biology of ecosystems and…

Single-cell DNA sequencing data analysis bioinformatics software tools

Most Recent Tools

Desktop app
G T A T C G C T A Canu Canu

Canu

Is specifically designed for noisy single-molecule sequences. Canu introduces…

Is specifically designed for noisy single-molecule sequences. Canu introduces support for nanopore sequencing, halves depth-of-coverage requirements, and improves assembly continuity while…

Web app
Desktop app
G T A T C G C T A Automated… Automated Contamination Detection and Confidence…

ACDC Automated Contamination Detection and Confidence estimation

Detects both known and de novo contaminants. ACDC was specifically developed to…

Detects both known and de novo contaminants. ACDC was specifically developed to aid the quality control process of genomic sequence data. First, 16S rRNA gene prediction and the inclusion of…

Desktop app
G T A T C G C T A smrt pipeline smrt pipeline

smrt pipeline

Enables recovery of high identity allele structures for the sequence regions…

Enables recovery of high identity allele structures for the sequence regions whose length was confirmed by Polymerase Chain Reaction (PCR) from cell line genomic DNA. smrt_pipeline is a method for…

Desktop app
G T A T C G C T A SiFit SiFit

SiFit

Reconstructs phylogenetic tree from noisy mutation profile of single cells.…

Reconstructs phylogenetic tree from noisy mutation profile of single cells. SiFit employs a heuristic search algorithm to infer the Maximum Likelihood (ML) phylogenetic tree under a finite-site model…

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