A specialized databank for chemically modified siRNAs. siRNAmod contains a total of 4894 chemically modified-siRNA sequences, comprising 128 unique chemical modifications on different positions with various permutations and combinations. It incorporates important information on siRNA sequence, chemical modification, their number and respective position, structure, simplified molecular input line entry system canonical (SMILES), efficacy of modified siRNA, target gene, cell line, experimental methods, reference etc. siRNAmod browsing option helps user to surf via these five categories: i) modification in sense strand, ii) position of modification in sense strand, iii) modification in antisense strand, iv) position of modification in antisense strand and v) reference.
Bioinformatics Centre, Institute of Microbial Technology, Council of Scientific and Industrial Research, Chandigarh, India
siRNAmod funding source(s)
Financial support for this work is provided by CSIR-Institute of Microbial Technology (OLP 0083), Council of Scientific and Industrial Research (BSC0121) and Department of Biotechnology, Government of India (GAP0001).