SLITHER statistics

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Citations per year

Number of citations per year for the bioinformatics software tool SLITHER

Tool usage distribution map

This map represents all the scientific publications referring to SLITHER per scientific context
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Associated diseases


Popular tool citations

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SLITHER specifications


Unique identifier OMICS_07214
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for SLITHER

SLITHER citations


Deorphanizing the human transmembrane genome: A landscape of uncharacterized membrane proteins

Acta Pharmacol Sin
PMCID: 3880479
PMID: 24241348
DOI: 10.1038/aps.2013.142

[…] dimensional structure correlated with classifications or functional parameters, methods have also been developed to directly infer function based on a three dimensional conformation. For example, the SLITHER program uses molecular modeling simulations to predict whether a putative substrate molecule may permeate the cavities or channels in a protein structure. In cases where the existence of a cha […]


Structural Analysis of Prolyl Oligopeptidases Using Molecular Docking and Dynamics: Insights into Conformational Changes and Ligand Binding

PLoS One
PMCID: 3223163
PMID: 22132071
DOI: 10.1371/journal.pone.0026251

[…] Cleavage of any small peptide like angiotensin-IV by POP produces two N- and C-terminal products. SLITHER generates contiguous conformations of ligand across the tunnel. Docking of smaller product in porcine POP (C-terminal) by SLITHER showed that its egress can be through β-propeller pore. Diffe […]

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SLITHER institution(s)
Division of Mechanics, Research Center for Applied Sciences, Academia Sinica, Taipei, Taiwan

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