SMA protocols

SMA specifications


Unique identifier OMICS_27096
Name SMA
Alternative name Single Marker Association
Software type Application/Script
Interface Command line interface
Restrictions to use None
Input format SNP
Operating system Unix/Linux, Mac OS
Programming languages C++
License GNU General Public License version 3.0
Computer skills Advanced
Version 1.2.1-1
Stability Stable
Requirements Boost Library, GNU Scientific Library, SNPfile library
Source code URL
Maintained Yes



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  • person_outline Thomas Mailund <>

SMA IN pipelines

PMCID: 4973970
PMID: 27490946
DOI: 10.1371/journal.pone.0159609

[…] confident variants remained with a minimal coverage of >59x and with a transition/transversion ratio ti/tv = 2.52, indicative of a relatively high true-positive rate for our dataset[10,9]., single marker association and gene-based analyses (p-value = 9.2 x 10−5) showed an association of the muc2 gene with uc in the dutch population (table 3). muc2 was selected because it induces […]

PMCID: 3612041
PMID: 23555951
DOI: 10.1371/journal.pone.0060301

[…] the joslin diabetes center in accordance with the manufacturer's protocols., each snp was tested for deviation from hardy-weinberg equilibrium using a chi-square goodness-of-fit test. family-based single-marker association tests were performed using the fbat software under an additive model using a conservative empirical variance estimator to test the null hypothesis of no linkage […]

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