SNPdryad specifications

Information


Unique identifier OMICS_02198
Name SNPdryad
Interface Web user interface
Restrictions to use None
Input data A non-synonymous human SNP and the sequence of the human protein that the SNP is on.
Output data A predicted deleterious score for the input nsSNP.
Computer skills Basic
Stability No
Maintained No

Taxon


  • Primates
    • Homo sapiens

Maintainer


This tool is not available anymore.

Publication for SNPdryad

SNPdryad citations

 (2)
library_books

Epileptogenic Brain Malformations and Mutations in Tubulin Genes: A Case Report and Review of the Literature

2017
Int J Mol Sci
PMCID: 5713243
PMID: 29109381
DOI: 10.3390/ijms18112273

[…] e, available online: http://evs.gs.washington.edu/EVS), with a minor allele frequency >0.01 (1%), were dropped. In silico prediction of mutations’ pathogenicity was obtained using the MutationTaster, SNPdryad, and PolyPhen2 databases (Hong Kong, China). Putative causative variants were analyzed by Sanger sequencing to confirm the next-generation sequencing results and were investigated in the pare […]

library_books

A Novel Approach to Predict Core Residues on Cancer Related DNA Binding Domains

2016
Cancer Inform
PMCID: 4892203
PMID: 27279732
DOI: 10.4137/CIN.S39366

[…] map the positions back to the structural data as shown in , interestingly, they correspond to the region where the protein-DNA binding occurs, explaining the enrichment of harmful nsSNPs predicted by SNPdryad. […]

SNPdryad institution(s)
Department of Computer Science, University of Toronto, Toronto, ON, Canada; The Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada; Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
SNPdryad funding source(s)
Supported by Natural Sciences and Engineering Research Council, Canada (NSERC), grant number [327612-2009 RGPIN]; Acres Inc. - Joseph Yonan Memorial Fellowship, Kwok Sau Po Scholarship, and International Research and Teaching Assistantship from University of Toronto.

SNPdryad reviews

 (3)
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Anonymous user #484's avatar image No country

Anonymous user #484

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Web
Proteomic wide predictions can be downloaded from this website. It is very convenient.
Anonymous user #483's avatar image No country

Anonymous user #483

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Web
The website is very user-friendly. I highly recommend it.