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SNPexp specifications

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Unique identifier OMICS_22600
Name SNPexp
Interface Web user interface
Restrictions to use None
Programming languages Perl
License Other
Computer skills Basic
Stability No
Maintained No

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Publication for SNPexp

SNPexp citations

 (29)
library_books

Genetic variants in the nucleotide excision repair pathway genes and gastric cancer susceptibility in a southern Chinese population

2018
PMCID: 5903836
PMID: 29695933
DOI: 10.2147/CMAR.S160080

[…] molecular mechanisms. the genotype data for 270 individuals were collected from hapmap. ercc1 mrna expression levels of lymphoblastoid cell lines from the same 270 individuals were extracted from snpexp. we observed that genotypes of the rs2298881 c>a polymorphism were significantly correlated with decreased ercc1 mrna expression in chinese subjects (p=0.003), africans (p<0.0001), […]

library_books

The single nucleotide polymorphisms in CHD5 affect the prognosis of patients with hepatocellular carcinoma

2017
Oncotarget
PMCID: 5862573
PMID: 29568352
DOI: 10.18632/oncotarget.23812

[…] from 270 individuals of four ethnic groups (chb, jpt, ceu, and yri) and chd5 mrna expression levels from ebv-transformed b lymphoblastoid cell lines from the same 270 individuals available by snpexp []. finally, least squares analysis of variance (anova) was performed to calculate statistical levels of chd5 transcripts expression according to different haplotypes., all statistical tests […]

library_books

Polymorphisms in nucleotide excision repair genes and risk of primary prostate cancer in Chinese Han populations

2016
Oncotarget
PMCID: 5421853
PMID: 27974699
DOI: 10.18632/oncotarget.13848

[…] were not observed in african ancestry in southwest (asw) and ceu, but in asian populations (i.e., han chinese and japanese) (hapmap data rel 27 phase ii+iii). in addition, according to an online snpexp server system (http://app3.titan.uio.no/biotools), significant differences on xpc mrna expression levels among populations carrying the wild homozygous genotypes were observed (student t-test, […]

library_books

Genetic dissection of host immune response in pneumonia development and progression

2016
Sci Rep
PMCID: 5057148
PMID: 27725770
DOI: 10.1038/srep35021

[…] in association with cytokine expression., further we performed an in silico analysis of correlation between interleukin and toll-like receptor genotypes and basal gene expression levels utilizing snpexp resource. we constructed haplotypes with the haploview software and analyzed association between check snps in haplotype blocks and mrna expression levels in lymphoblastoid cell lines […]

library_books

Association between a functional variant in RAD51 gene’s 3′ untranslated region and its mRNA expression in lymphoblastoid cell lines

2016
Springerplus
PMCID: 5042920
PMID: 27733989
DOI: 10.1186/s40064-016-3339-2

[…] (http://www.snpinfo.niehs.nih.gov/cgi-bin/snpinfo/snpfunc.cgi)., we used additional data on rad51 genotypes and mrna levels available online (http://www.app3.titan.uio.no/biotools/help.php?app=snpexp) for the genotype-phenotype association analysis (holm et al. ). we used genome-wide expression arrays (47,294 transcripts) from epstein–barr virus-transformed lymphoblastoid cell lines […]

library_books

MDM4 rs4245739 A > C polymorphism correlates with reduced overall cancer risk in a meta analysis of 69477 subjects

2016
Oncotarget
PMCID: 5342115
PMID: 27687591
DOI: 10.18632/oncotarget.12326

[…] > c polymorphism for 270 individuals with three ethnicities were obtained from hapmap (http://www.hapmap.org). the mdm4 gene mrna expression data for the same 270 individuals were downloaded from snpexp (http://app3.titan.uio.no/biotools/tool.php?app=snpexp)., the strength of the association between mdm4 rs4245739 a > c polymorphism and overall cancer risk were assessed using crude […]


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SNPexp institution(s)
Norwegian PSC Research Center, Clinic for Specialized Medicine and Surgery, Oslo University Hospital Rikshospitalet, Oslo, Norway; Research Institute for Internal Medicine, Clinic for Specialized Medicine and Surgery, Oslo University Hospital Rikshospitalet, Oslo, Norway; Institute for Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany

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