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Performs linkage and association mappings of the quantitative trait loci (QTLs) in pedigrees of arbitrary size and complexity. solarius allows the user to exploit the variance component methods implemented in SOLAR. It automates such routine operations as formatting pedigree and phenotype data. It also parses the model output and contains summary and plotting functions for exploration of the results. In addition, solarius enables parallel computing of the linkage and association analyses, that makes the calculation of genome-wide scans more efficient.

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solarius specifications

Software type:
Package
Restrictions to use:
None
Programming languages:
R
Computer skills:
Advanced
Stability:
Stable
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
License:
GNU General Public License version 3.0
Version:
solarius version 0.3.0.2
Source code URL:
https://github.com/ugcd/solarius

solarius support

Documentation

Maintainer

Credits

Publications

Institution(s)

Unitat de Genòmica de Malalties Complexes, Institut d’Investigació Biomèdica Sant Pau (IIB-Sant Pau), Barcelona, Spain; Department of Genetics Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; B2SLab, Department d’Enginyeria de Sistemes, Automàtica i Informàtica Industrial, Universitat Politècnica de Catalunya, Barcelona, Spain; CIBER in Bioengineering, Biomaterials and Nanomedicine, Spain

Funding source(s)

This research was funded by the TEC2013-44666-R grant. This work was partially funded by the 2014SGR-2016 consolidated research group of the Generalitat de Catalunya, Spain. CIBER-BBN is an initiative of the Spanish ISCIII. This research was supported partially by grants PI-11/0184, PI-14/0582 and UIN2013-50833 from the Instituto Carlos III (Fondo de Investigación Sanitaria - FIS).

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