1. Directory
  2. Genomics
  3. Genome annotation
  4. Repetitive DNA
Join community Sign in
By using OMICtools you acknowledge that you have read and accepted the terms of the end user license agreement.

A database of cancer somatic mutations in microRNAs (miRNA) and their target sites that potentially alter the interactions between miRNAs and competing endogenous RNAs (ceRNA) including mRNAs, circular RNAs (circRNA) and long noncoding RNAs (lncRNA). We expanded the scope of the database by including somatic mutations that impact the interactions between miRNAs and two classes of non-coding RNAs, circRNAs and lncRNAs. A recently developed webserver, miR2GO, was integrated with the database to provide a seamless pipeline for assessing functional impacts of somatic mutations in miRNA seed regions. Data and functions from multiple sources including biological pathways and genome-wide association studies were updated and integrated with SomamiR 2.0 to make it a better platform for functional analysis of somatic mutations altering miRNA-ceRNA interactions.

Restrictions to use:
None
Version:
SomamiR version 2.0
View all reviews

0 user review

No review has been posted.

View all issues

0 issue

No open issue.

Maintainer

  • Anindya Bhattacharya <anindyamail123 at gmail.com>

Institution(s)

Machine Intelligence Unit, Indian Statistical Institute, Kolkata, WB 700108, India; Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Center for Integrative and Translational Genomics, University of Tennessee Health Science Center, Memphis, TN 38163, USA

Funding source(s)

The Ramalingaswami Re-entry fellowship, Department of Biotechnology, India [Project Title: Functional Annotation of Somatic Mutations in Cancer, Project Number: BT/RLF/Re-entry/09/2013]

  • (Bhattacharya and Cui, 2015) SomamiR 2.0: a database of cancer somatic mutations altering microRNA-ceRNA interactions. Nucleic acids research.
    PMID: 26578591
  • (Bhattacharya et al., 2013) SomamiR: a database for somatic mutations impacting microRNA function in cancer. Nucleic acids research.
    PMID: 23180788
  • Animals
    • Homo sapiens
  • (Pavlopoulou et al., 2015) Human cancer databases (review). Oncology reports.
    PMID: 25369839

99 related tools