SIFT specifications

Unique identifier:
OMICS_00137
Alternative names:
SIFT for genomes, SIFT 4G
Interface:
Command line interface
Input data:
Some sequence conservation and amino acid properties.
Output format:
VCF,XLS
License:
GNU General Public License version 3.0
Version:
2.0.0
Requirements:
g++, GNU make, nvcc
Name:
Sorting Intolerant From Tolerant
Software type:
Application/Script
Restrictions to use:
None
Input format:
VCF,FASTA,GTF,GFF
Operating system:
Unix/Linux
Computer skills:
Advanced
Stability:
Stable
Maintained:
Yes
  • Animals
    • Homo sapiens

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SIFT distribution

download

SIFT specifications

Unique identifier:
OMICS_00137
Alternative names:
SIFT for genomes, SIFT 4G
Restrictions to use:
None
Input format:
VCF
Computer skills:
Basic
Maintained:
Yes
Name:
Sorting Intolerant From Tolerant
Interface:
Web user interface
Input data:
Some sequence conservation and amino acid properties.
Output format:
VCF,XLS
Stability:
Stable
  • Animals
    • Homo sapiens

SIFT support

Maintainer

  • Pauline Ng <>
  • Pauline Ng <>

Additional information

http://sift.jcvi.org/

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Credits

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Publications

Institution(s)

Faculty of Electrical Engineering and Computing, University of Zagreb, Zagreb, Croatia; Computational and Systems Biology Group, Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore; Bioinformatics Institute, Agency for Science, Technology and Research, Singapore, Singapore

Funding source(s)

Supported in part by A*STAR and the Croatian Science Foundation (project no. 7353, Algorithms for Genome Sequence Analysis).

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Julio Diaz Caballero's avatar image

Julio Diaz Caballero

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The web interface of this software runs smoothly and relatively fast. The output is simple to understand and it is summarized In a single value (SIFT score). Nonetheless, I wanted to run a batch of predictions and tried to download and install SIFT in my computer, but that turned out to be a very difficult process. The dependencies are old and difficult to install. I emailed the author in order to get some assistance, but no reply. I think they stopped supporting SIFT in favour of PROVEAN.

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