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SOSUI specifications


Unique identifier OMICS_07263
Interface Web user interface
Restrictions to use None
Input data A protein sequence
Output data Membrane proteins
Computer skills Basic
Stability Stable
Maintained Yes

Publications for SOSUI

SOSUI citations


A single amino acid substitution in the Bombyx specific mucin like membrane protein causes resistance to Bombyx mori densovirus

Sci Rep
PMCID: 5943349
PMID: 29743532
DOI: 10.1038/s41598-018-25388-7
call_split See protocol

[…] NCBI-blastp (, Pfam (, and SOSUI ( were used to search for motifs in the NSD-1 sequence. […]


The Ancient Link between G Protein Coupled Receptors and C Terminal Phospholipid Kinase Domains

PMCID: 5784254
PMID: 29362235
DOI: 10.1128/mBio.02119-17

[…] lyzed for protein domain composition using the SMART database () and Pfam, Prints, and TIGRFAMs under InterProScan (). TM domains were predicted using Phobius (), TMHMM (), HMMTOP (), GPCRHMM (), and SOSUI (). Proteins containing domains other than PIPK at the C terminus and those without TM domains were discarded. Newly identified GPCR-PIPKs were then used in queries for iterative searches using […]


Complete Genome Sequence of Streptomyces Bacteriophage Abt2graduatex2

Genome Announc
PMCID: 5773734
PMID: 29348349
DOI: 10.1128/genomeA.01480-17

[…] h which it shares an average nucleotide identity (ANI) of 73% (GenBank accession number KU530220).Abt2graduatex2 gp29 has been identified as a putative class II holin () by structural homology () and SOSUI analysis showing two transmembrane regions (). Abt2graduatex2 gp29 is present in all current members of the BG cluster, where it forms a putative operon with gp28, a lysin, but it is absent in a […]


Interspecies diversity of chloride channel regulators, calcium activated 3 genes

PLoS One
PMCID: 5773202
PMID: 29346439
DOI: 10.1371/journal.pone.0191512

[…] The amino acid sequences of the feline CLCA3 were analyzed in silico using the SignalP 4.1 [], Kyte–Doolittle [], SOSUI [], HMMtop [], DAS [], PSORT II [] and NetNGlyc ( software. Putative proteolytic cleavage sites were identified by interspecies comparison of the amino ac […]


A novel galactolipase from a green microalga Chlorella kessleri: purification, characterization, molecular cloning, and heterologous expression

Appl Microbiol Biotechnol
PMCID: 5794828
PMID: 29299622
DOI: 10.1007/s00253-017-8713-7

[…] et al. ). ckGL was unstable in the absence of Triton X-100, suggesting that it might be membrane-bound or associated. As discussed above, the ChloroP program predicted that ckGL has a cTP, while the SOSUI system and TMHMM server analyses of ckGL suggested that the enzyme is a soluble protein. Therefore, these results imply that ckGL might be located in the chloroplast stroma. Further investigatio […]


A Disulfide Bond in the Membrane Protein IgaA Is Essential for Repression of the RcsCDB System

Front Microbiol
PMCID: 5744062
PMID: 29312270
DOI: 10.3389/fmicb.2017.02605

[…] murium showed that IgaA is an inner membrane protein produced at relatively constant levels in all growing conditions (). Programs that predict transmembrane helix regions and protein topology (THMM, SOSUI, TMPred, PredictProtein) indicate that the 710 amino acid protein IgaA has five transmembrane segments, resulting in two cytosolic domains (residues 22–202, 247–336), one small periplasmic loop […]

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SOSUI institution(s)
Tokyo University of Agriculture and Technology, Faculty of Technology, Department of Biotechnology, Tokyo, Japan; Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan
SOSUI funding source(s)
This study was partly supported by a grant-in-aid for special projects in genome science from the Ministry of Education, Sports, Science and Technology.

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