SpacePAC statistics

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Citations per year

Number of citations per year for the bioinformatics software tool SpacePAC
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Tool usage distribution map

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Associated diseases

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SpacePAC specifications

Information


Unique identifier OMICS_19678
Name SpacePAC
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License GNU General Public License version 2.0
Computer skills Advanced
Version 1.18.3
Stability Stable
Requirements
BiocGenerics, R(>=2.15), RUnit, rgl, iPAC
Maintained Yes

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Versioning


No version available

Documentation


Maintainers


  • person_outline Hongyu Zhao
  • person_outline Gregory Ryslik

Publication for SpacePAC

SpacePAC citation

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3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets

2017
Genome Med
PMCID: 5260099
PMID: 28115009
DOI: 10.1186/s13073-016-0393-x

[…] studied enrichment of mutations in protein-protein interaction interfaces. StructMAn [] annotated the amino acid variations of single-nucleotide polymorphisms (SNPs) in the context of 3D structures. SpacePAC [], Mutation3D [], HotMAPS [], and Hotspot3D [] used 3D structures to identify mutational clusters in cancer. These efforts have generated interesting sets of candidate functional mutations a […]


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SpacePAC institution(s)
Department of Biostatistics, Yale School of Public Health, New Haven, CT, USA; Program of Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA; Yale Center for Medical Informatics, Yale School of Medicine, New Haven, CT, USA; Department of Computer Science, Yale University, New Haven, CT, USA; Department of Molecular Biophysics & Biochemistry, Yale University, New Haven, CT, USA
SpacePAC funding source(s)
Supported in part by NSF Grant DMS 1106738, NIH Grants GM59507 and CA154295, and GM102869.

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