Organizes lipids into eight well-defined categories that cover eukaryotic and prokaryotic sources. LIPID MAPS filters data in functional hierarchies involving lipids, reactions, and pathways. It is a multi-institutional effort created in 2003 and uses a systems biology approach and sophisticated mass spectrometers (MS), all of the major — and many minor — lipid species in mammalian cells. The database quantitates the changes in species in response to perturbation.
Current tandem mass spectral libraries for lipid annotations in metabolomics are limited in size and diversity. LipidBlast is a freely available computer-generated tandem mass spectral library of 212,516 spectra covering 119,200 compounds from 26 lipid compound classes, including phospholipids, glycerolipids, bacterial lipoglycans and plant glycolipids.
Gathers structures and annotations of biologically relevant lipids. LMSD is a database of lipids that has several features: (i) usage of hierarchical classification and consistent nomenclature based on a comprehensive classification scheme proposed by LIPID MAPS, (ii) a unique LIPID MAPS identifier (LM ID) assignment to all structures, (iii) no duplicate structures and, (iv) ability to search database using structure.
A knowledge resource for lipids and their biology. SwissLipids provides curated knowledge of lipid structures and metabolism which is used to generate an in silico library of feasible lipid structures. These are arranged in a hierarchical classification that links mass spectrometry analytical outputs to all possible lipid structures, metabolic reactions, and enzymes. SwissLipids provides a reference namespace for lipidomic data publication, data exploration and hypothesis generation.
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