SPICE statistics

info info

Citations per year

Number of citations per year for the bioinformatics software tool SPICE
info

Tool usage distribution map

This map represents all the scientific publications referring to SPICE per scientific context
info info

Associated diseases

This word cloud represents SPICE usage per disease context
info

Popular tool citations

chevron_left Flow cytometry data visualization Normalization chevron_right
Want to access the full stats & trends on this tool?

Protocols

SPICE specifications

Information


Unique identifier OMICS_05645
Name SPICE
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes

Versioning


No version available

Publication for SPICE

SPICE citations

 (154)
library_books

Transcriptomic signatures of NK cells suggest impaired responsiveness in HIV 1 infection and increased activity post vaccination

2018
Nat Commun
PMCID: 5865158
PMID: 29572470
DOI: 10.1038/s41467-018-03618-w

[…] All flow data were analyzed in FlowJo LLC, Treestar Inc. (Ashland, OR), and then permutation tests were performed to determine statistical significance in comparison of pie charts generated in Spice software (Bethesda, MD). Volcano plots of the HTA data were generated using an affymetrix data table containing adjusted p-values and fold change pre-calculated by Affymetrix® TAC Software. Affy […]

call_split

Expansion of Gammadelta T Cells from Cord Blood: A Therapeutical Possibility

2018
PMCID: 5863314
PMID: 29707004
DOI: 10.1155/2018/8529104
call_split See protocol

[…] ctor of 150 in CYT for comparability, and subsamples of 5000 events were obtained randomly from the sample files before bh-SNE analysis.The analysis of viability and apoptosis was performed using the SPICE software [], which generated graphics illustrating the differences in the proportion of dead and apoptotic cells between the groups, and the statistical analysis was performed using the built-in […]

call_split

Functional, Antigen Specific Stem Cell Memory (TSCM) CD4+ T Cells Are Induced by Human Mycobacterium tuberculosis Infection

2018
Front Immunol
PMCID: 5839236
PMID: 29545791
DOI: 10.3389/fimmu.2018.00324
call_split See protocol

[…] Flow cytometry data was analyzed using FlowJo (Tree Star) versions v9.7 to v10.1r.1, Pestle version 1.8, and SPICE version 5.2–5.3 ().Threshold cycle (Ct) values were determined by the BioMark Real-time PCR Analysis software using linear derivative background correction and an amplification curve quality thr […]

call_split

Cytomegalovirus specific T cells are associated with immune senescence, but not with systemic inflammation, in people living with HIV

2018
Sci Rep
PMCID: 5830877
PMID: 29491459
DOI: 10.1038/s41598-018-21347-4
call_split See protocol

[…] ), we analysed the magnitude of the total CMV-specific response (%CD8+ or %CD4+). Thus, each responding cell was calculated only once. Polyfunctionality visualization and analysis was performed using Spice Version 4.2.3 (Mario Roederer, ImmunoTechnology Section, VRC/NIAID/NIH) software. […]

call_split

Human Immunodeficiency Virus Type 1 Elite Controllers Maintain Low Co Expression of Inhibitory Receptors on CD4+ T Cells

2018
Front Immunol
PMCID: 5786543
PMID: 29403500
DOI: 10.3389/fimmu.2018.00019
call_split See protocol

[…] or gating analysis, and statistical analysis was performed with GraphPad Prism 6.0. Analysis and graphical representation of cell surface inhibitory markers were conducted using data analysis program SPICE (version 5.35001) (). […]

call_split

Safety and Immunogenicity of Malaria Vectored Vaccines Given with Routine Expanded Program on Immunization Vaccines in Gambian Infants and Neonates: A Randomized Controlled Trial

2017
Front Immunol
PMCID: 5702785
PMID: 29213269
DOI: 10.3389/fimmu.2017.01551
call_split See protocol

[…] cies. Pie charts were generated using relative frequencies with a threshold of 0.004% of the parent population. Data analysis was performed using FlowJo v10.1r1 (Treestar Inc., USA), Pestle v1.7, and Spice v5.3 (Mario Roederer, Vaccine Research Centre, NIAID, NIH, USA). […]


Want to access the full list of citations?
SPICE institution(s)
Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA

SPICE reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review SPICE