SPIN specifications


Unique identifier OMICS_11249
Alternative name Simultaneous Protein Interaction Network
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Windows
Programming languages Java
License GNU General Public License version 3.0
Computer skills Advanced
Version 1.3
Stability Stable
Maintained Yes


No version available


  • person_outline Dong-Soo Han

Publication for Simultaneous Protein Interaction Network

SPIN citations


Protein Complex Identification by Integrating Protein Protein Interaction Evidence from Multiple Sources

PLoS One
PMCID: 3873956
PMID: 24386289
DOI: 10.1371/journal.pone.0083841

[…] les to help refine the putative complexes . With this method, the running time is proportional to the number of samples and could become a concern if the PPI network is large. Jung et al presented a simultaneous protein interaction network, which deleted any mutually exclusive interactions based on domain information. Ozawa et al also considered the competition between mutually exclusive interac […]


Efficient and accurate greedy search methods for mining functional modules in protein interaction networks

BMC Bioinformatics
PMCID: 3314584
PMID: 22759424
DOI: 10.1186/1471-2105-13-S10-S19

[…] e weights are above a given threshold. However, since the highly weighted vertices may not be highly connected to each other, the algorithm does not guarantee that the discovered regions are dense. A simultaneous protein interaction network (SPIN) introduced by Jung et al [] specifies mutually exclusive interactions (MEIs). Taking advantages of the SPINs, SPIN_MCODE has outperformed the plain MCOD […]

SPIN institution(s)
Department of Information & Communications Engineering, Korea Advanced Institute of Science and Technology, Yuseong-gu, Daejeon, Korea; Department of Computer Science, Korea Advanced Institute of Science and Technology, Yuseong-gu, Daejeon, Korea
SPIN funding source(s)
Korea government (MEST) (Korea Science and Engineering Foundation No. 2008-0061123)

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