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SplicingCompass | Differential splicing detection using RNA-seq data

A package to predict genes that are differentially spliced between two different conditions using RNA-seq data. This method allows users to detect tissue-specific alternative splicing in brain versus liver samples and tumour stage-specific alternative splicing in neuroblastoma patients. SplicingCompass reduces the number of statistical tests considerably and better accounts for combined effects..

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SplicingCompass classification

  • Animals
    • Homo sapiens

SplicingCompass specifications

Unique identifier:
Command line interface
Input data:
Read count and junctions
Operating system:
Unix/Linux, Mac OS, Windows
GNU General Public License version 2.0
Software type:
Restrictions to use:
Input format:
Programming languages:
Computer skills:

SplicingCompass distribution


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Bioinformatics HUSAR, Genomics Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg, Germany; Division of Theoretical Bioinformatics, DKFZ, Heidelberg, Germany; Department of Pediatric Oncology and Hematology and Center for Molecular Medicine Cologne (CMMC), University Children’s Hospital, Cologne, Germany; Department of Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, Bioquant, University of Heidelberg, Heidelberg, Germany; Center for Sepsis Control and Care, University Hospital Jena, Jena, Germany; Leibniz Institute for Natural Products Research and Infection Biology, Hans-Knoll-Institute, Jena, Germany

Funding source(s)

This project was supported by the Joint Germany-Israeli Research Program (ca-139) (DKFZ/MOST), the Nationales Genom-Forschungs-Netz (NGFN+), ENGINE (#01GS0898).

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