Reads paired 16-bit or 8-bit TIFF image files generated by most microarray scanners. TIGR Spotfinder is an image-processing software created for analysis of the image files generated in microarray expression studies. It uses a fast and reproducible algorithm to identify the spots in the array and provide quantification of expression levels. Spotfinder was designed for the rapid, reproducible and computer-aided analysis of microarray images and the quantification of gene expression. Spotfinder is part of TM4 Microarray software.