SPRITE specifications


Unique identifier OMICS_08533
Alternative name 3D Search for PRotein sITEs
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Mohd Firdaus-Raih

Publication for 3D Search for PRotein sITEs

SPRITE citations


Structure and context based analysis of the GxGYxYP family reveals a new putative class of Glycoside Hydrolase

BMC Bioinformatics
PMCID: 4071793
PMID: 24938123
DOI: 10.1186/1471-2105-15-196

[…] hes of the PDB. The crystal structure was submitted to ProFunc [] for several structure-based analyses. Searches for 3D structural motifs representing catalytic or other binding sites were done using SPRITE [] and PINTS []. The POOL server [] was used to predict catalytic residues by integrating analyses of structure cavities and perturbed predicted pKa values []. Structures were visualised with P […]


Proteins of Unknown Function in the Protein Data Bank (PDB): An Inventory of True Uncharacterized Proteins and Computational Tools for Their Analysis

Int J Mol Sci
PMCID: 3497298
PMID: 23202924
DOI: 10.3390/ijms131012761

[…] that functional similarity can exist as an outcome of similar amino acid residues being clustered in 3D space that in turn gives rise to similar chemical activity. Search programs such as ProFunc and SPRITE/ASSAM take this factor into consideration where the target of a search can be directed at finding similar constellations of amino acids thus providing clues to similar chemical activity. At pre […]

SPRITE institution(s)
School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Bangi, Malaysia

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