SSFA-GPHR specifications

Information


Unique identifier OMICS_22344
Name SSFA-GPHR
Alternative name Sequence-Structure-Function-Analysis of Glycoprotein Hormone Receptors
Restrictions to use None
Database management system MySQL
Community driven No
Data access Browse
User data submission Not allowed
Maintained Yes

Maintainers


  • person_outline Gerd Krause
  • person_outline Gunnar Kleinau
  • person_outline Annika Kreuchwig

Publication for Sequence-Structure-Function-Analysis of Glycoprotein Hormone Receptors

SSFA-GPHR citation

library_books

Differences in Signal Activation by LH and hCG are Mediated by the LH/CG Receptor’s Extracellular Hinge Region

2015
PMCID: 4585211
PMID: 26441830
DOI: 10.3389/fendo.2015.00140

[…] ed in the LHCGR at LRRD repeat 10 (R247) and on the pivotal helix of Cb-3 (e.g., R283) and on beta strand-12 (K339, R342; see residues, mutations and models also at our GPHR information resource: www.SSFA-GPHR.de ()).This hypothesis is consistent with the results reported for an activating antibody 13B1 of the hinge region of LHCGR (), which interacts via a discontinuous sequence epitope comprisin […]

SSFA-GPHR institution(s)
Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin, Germany; Institute of Experimental Pediatric Endocrinology, Charité Universitätsmedizin Berlin, Germany

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