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starBase specifications


Unique identifier OMICS_06102
Name starBase
Restrictions to use None
Data access File download, Browse
Version 2.0
Maintained Yes


  • person_outline Jian-Hua Yang
  • person_outline Liang-Hu Qu

Publications for starBase

starBase citations


Identification of cancer related miRNA lncRNA biomarkers using a basic miRNA lncRNA network

PLoS One
PMCID: 5929565
PMID: 29715309
DOI: 10.1371/journal.pone.0196681

[…] , Wang et al. identified functional RNA pairs by computing the Pearson correlation coefficients and p-values based on expression profiles []. Zhang et al. developed a competing network using miRcode, StarBase and miRTarBase in HCC, with a focus on the hub nodes of the network []. In 2017, Guo et al. assessed the joint predictive power of miRNAs and lncRNAs using miRNA and lncRNA expression data, a […]


Distinct and Modular Organization of Protein Interacting Sites in Long Non coding RNAs

Front Mol Biosci
PMCID: 5893854
PMID: 29670884
DOI: 10.3389/fmolb.2018.00027

[…] nd the same has been reported recently by Wang and group (Wang et al., ) (Figure , Supplementary Figures , ).We further observed that AGO proteins across the three datasets, namely; Clipdb-PARalyzer, starBase, and doRiNA showed to have a positional preference in protein coding and lncRNA transcripts (Figures , ). When we examined the mapping for the three datasets in protein coding transcripts, we […]


Bioinformatic analysis and prediction of the function and regulatory network of long non coding RNAs in hepatocellular carcinoma

PMCID: 5934726
PMID: 29740493
DOI: 10.3892/ol.2018.8271

[…] may interact with miRNAs (). The results of previous studies have indicated that the interaction of lncRNAs and miRNAs serve a notable function in the progression of cancer (–). In the present study, starBase2.0 was used to predict the miRNAs that were associated with lncRNAs (HOTAIR, MALAT1 and HULC). However, no miRNA was identified to interact with HULC, so further analyses were performed on HO […]


Long non coding RNA XIST exerts oncogenic functions in pancreatic cancer via miR 34a 5p

PMCID: 5868395
PMID: 29393501
DOI: 10.3892/or.2018.6245

[…] lncRNAs communicate with other protein-coding RNA transcripts via shared common miRNA binding sites (). According to the ceRNA hypothesis, miRNA complementary base pairing with XIST was predicted by starBase and TargetScan, and miR-34a-5p was identified. Quantitative real-time PCR showed that the expression of miR-34a-5p in BxPC-3 cells was decreased upon overexpresion of XIST, however increased […]


Hsa_circ_0001859 Regulates ATF2 Expression by Functioning as an MiR 204/211 Sponge in Human Rheumatoid Arthritis

J Immunol Res
PMCID: 5822876
PMID: 29577053
DOI: 10.1155/2018/9412387
call_split See protocol

[…] top 500 scored RA-DEGs. miRWalk was used to predict the miRNAs that may downregulate the mRNAs of RA-DEGs (RA-miRNAs), and the interactions between candidate circRNAs and miRNAs were predicted by the StarBase v2.0 tool. Molecular interaction networks were constructed according to mRNA profiling analysis, miRNA target prediction, and functional clustering. Algorithms (TargetScan, miRanda, Pictar2, […]


LncRNA Gas5 acts as a ceRNA to regulate PTEN expression by sponging miR 222 3p in papillary thyroid carcinoma

PMCID: 5790480
PMID: 29423063
DOI: 10.18632/oncotarget.23336

[…] Previous reports demonstrated that lncRNA might act as a ceRNA to miRNA []. But accurate regulatory mechanisms of Gas5 remains unclear. Bioinformatics analysis (Starbase 2.0, RNA22) of miRNA recognition sequences on Gas5 revealed the presence of more than 30 miRNAs binding sites. Among them, miR-222-3p stood out through detailed survey, which was considered t […]

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starBase institution(s)
Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory for Biocontrol, Sun Yat-sen University, Guangzhou, China
starBase funding source(s)
Supported by the Ministry of Science and Technology of China, National Basic Research Program [No 2011CB811300]; the National Natural Science Foundation of China [31230042, 30900820, 81070589, 31370791]; the funds from Guangdong Province [S2012010010510, S2013010012457]; Project of Science and Technology New Star in ZhuJiang Guangzhou city [2012J2200025]; Fundamental Research Funds for the Central Universities [2011330003161070]; China Postdoctoral Science Foundation [200902348] and supported in part by the Guangdong Province Key Laboratory of Computational Science and the Guangdong Province Computational Science Innovative Research Team.

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