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Protocols

STRBase specifications

Information


Unique identifier OMICS_07825
Name STRBase
Alternative name Short Tandem Repeat DNA Internet DataBase
Restrictions to use None
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Maintainer


  • person_outline John Butler

Publication for Short Tandem Repeat DNA Internet DataBase

STRBase citations

 (15)
library_books

A Melanoma Lymph Node Metastasis with a Donor Patient Hybrid Genome following Bone Marrow Transplantation: A Second Case of Leucocyte Tumor Cell Hybridization in Cancer Metastasis

2017
PLoS One
PMCID: 5287451
PMID: 28146572
DOI: 10.1371/journal.pone.0168581

[…] than the validated dye channel specific analytical thresholds 23–40 RFU (relative fluorescence units) were scored as true alleles based on a) height and b) peak morphology ( http://www.cstl.nist.gov/strbase/multiplx.htm [,]. […]

call_split

SNP Miniplexes for Individual Identification of Random‐Bred Domestic Cats†

2016
PMCID: 5019183
PMID: 27122395
DOI: 10.1111/1556-4029.13026
call_split See protocol

[…] and NetPrimer (www.premierbiosoft.com/netprimer/index.html). Each primer pair was tested for potential primer dimers and secondary hairpin structures using the Auto Dimer software (www.cstl.nist.gov/strbase/AutoDimerHomepage/AutoDimerProgramHomepage.htm). All SNP and single base extension (SBE) primers (see below) were verified with the sequence databases at the National Center for Biotechnology […]

library_books

Genetic Diversity in the Lesser Antilles and Its Implications for the Settlement of the Caribbean Basin

2015
PLoS One
PMCID: 4598113
PMID: 26447794
DOI: 10.1371/journal.pone.0139192

[…] enetic relationships among Y-chromosomes from indigenous Caribbean and South American populations. In the MJ network analysis, each Y-STR locus was weighed according to its mutation rate as listed in STRBase [], with slower rates given more weight than those with faster rates. In the coalescence analysis, we used an evolutionary mutation rate (EMR) of 2.8 x10-5 mutations per locus per year [], one […]

library_books

Novel Y chromosome Short Tandem Repeat Variants Detected Through the Use of Massively Parallel Sequencing

2015
PMCID: 4610967
PMID: 26391384
DOI: 10.1016/j.gpb.2015.08.001

[…] s/molecular-and-medical-genetics/laboratory-faculty-and-staff/strait-razor/). These unique sequences then were compared to the known sequences for those alleles that have been previously published in STRBase (http://www.cstl.nist.gov/strbase/srm2395.htm and http://www.cstl.nist.gov/strbase/srm2395.htm) and the literature .Y-STR haplogroups were predicted from the repeat lengths (i.e., operationall […]

library_books

Fabry disease: Evidence for a regional founder effect of the GLA gene mutation 30delG in Brazilian patients

2014
PMCID: 5121364
PMID: 27896116
DOI: 10.1016/j.ymgmr.2014.09.002

[…] Primers were designed using PRIMER3 and AUTO DIMER CHECK software (http://www.genome.wi.mit.edu/cgi-bin/primer/primer3) and (http://www.cstl.nist.gov/biotech/strbase/AutoDimerHomepage). The sequences of each primer, the concentrations used in the multiplex, marked fluorochromes (dye-labeling), and the size variation of each amplicon are presented in .Ampli […]

library_books

The nucleic acid revolution continues – will forensic biology become forensic molecular biology?

2014
Front Genet
PMCID: 3942684
PMID: 24634675
DOI: 10.3389/fgene.2014.00044

[…] tandem repeats (STRs) by multiplex PCR, followed by capillary electrophoresis. See for example and the website of the National Institute of Standards and Technology (http://www.cstl.nist.gov/biotech/strbase/multiplx.htm) for an extensive (but by no means complete) catalog of available markers. Furthermore, these relatively stable DNA markers are transmitted by classical Mendelian genetics, which […]

Citations

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STRBase institution(s)
Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD, USA

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